Preferred Name |
Actin Filament |
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Synonyms |
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Definitions |
"A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732, PMID:10666339] |
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ID |
http://www.phoc.org.cn/pmo/class/PMO_00054724 |
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Database_Cross_Reference |
GO:0005884 |
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Definition |
"A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732, PMID:10666339] |
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Gene Annotation |
RCSD1(UniProtKB:Q6JBY9) AIF1L(UniProtKB:Q9BQI0) VPS18(UniProtKB:Q9P253) PALLD(UniProtKB:Q8WX93) PLS3(UniProtKB:P13797) RAC1(UniProtKB:P63000) TPM3(UniProtKB:P06753) LMOD1(UniProtKB:P29536) FMN1(UniProtKB:Q68DA7) RAC2(UniProtKB:P15153) PLS1(UniProtKB:Q14651) TEK(UniProtKB:Q02763) IQGAP1(UniProtKB:P46940) MYO6(UniProtKB:Q9UM54) GDPD2(UniProtKB:Q9HCC8) TMOD1(UniProtKB:P28289) WASL(UniProtKB:O00401) AMOT(UniProtKB:Q4VCS5) ACKR2(UniProtKB:O00590) DMTN(UniProtKB:Q08495) POF1B(UniProtKB:Q8WVV4) MISP(UniProtKB:Q8IVT2) ACTN3(UniProtKB:Q08043) DAPK3(UniProtKB:O43293) AKAP13(UniProtKB:Q12802) TWF1(UniProtKB:Q12792) FYN(UniProtKB:P06241) ACTA1(UniProtKB:P68133) MYO9B(UniProtKB:Q13459) CORO1B(UniProtKB:Q9BR76) LCP1(UniProtKB:P13796) FKBP15(UniProtKB:Q5T1M5) TIGD5(UniProtKB:Q53EQ6) WIPF3(UniProtKB:A6NGB9) PAWR(UniProtKB:Q96IZ0) MYO5A(UniProtKB:Q9Y4I1) WIPF1(UniProtKB:O43516) ACTN2(UniProtKB:P35609) EZR(UniProtKB:P15311) MYO1B(UniProtKB:O43795) WHRN(UniProtKB:Q9P202) GAS2(UniProtKB:O43903) ACTN1(UniProtKB:P12814) WIPF2(UniProtKB:Q8TF74) TWF2(UniProtKB:Q6IBS0) ACTC1(UniProtKB:P68032) PSTPIP1(UniProtKB:O43586) TPM4(UniProtKB:P67936) TSC1(UniProtKB:Q92574) GAS7(UniProtKB:O60861) SHROOM4(UniProtKB:Q9ULL8) FLNA(UniProtKB:P21333) POTEKP(UniProtKB:Q9BYX7) LMOD2(UniProtKB:Q6P5Q4) WAS(UniProtKB:P42768) COBL(UniProtKB:O75128) CTTN(UniProtKB:Q14247) GNG12(UniProtKB:Q9UBI6) MARK2(UniProtKB:Q7KZI7) ACTG1(UniProtKB:P63261) CORO1A(UniProtKB:P31146) RHOQ(UniProtKB:P17081) HCK(UniProtKB:P08631) TPM2(UniProtKB:P07951) DNAJA3(UniProtKB:Q96EY1) TPM1(UniProtKB:P09493) SH2B2(UniProtKB:O14492) KEAP1(UniProtKB:Q14145) BIN3(UniProtKB:Q9NQY0) ANXA1(UniProtKB:P04083) APC2(UniProtKB:O95996) AIF1(UniProtKB:P55008) PAK1(UniProtKB:Q13153) ARHGAP6(UniProtKB:O43182) SRC(UniProtKB:P12931) PSTPIP2(UniProtKB:Q9H939) YES1(UniProtKB:P07947) |
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label |
Actin Filament |
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MCID |
MC04787814 |
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PMOID |
PMO:00054724 |
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prefixIRI |
pmo:PMO_00054724 |
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prefLabel |
Actin Filament |
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Synonym |
"microfilament" EXACT [] |
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Tree Number |
T10.3.7.100.34.16.12.4 T10.3.14.13.16.12.4 T10.3.18.4.2.4.4 |
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subClassOf |