Orphanet Rare Disease Ontology

Last uploaded: December 13, 2023
Preferred Name

Small cell lung cancer

Synonyms

SCLC

Definitions

Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized by rapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure.

ID

http://www.orpha.net/ORDO/Orphanet_70573

alternative_term

SCLC

definition

Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized by rapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure.

definition_citation

Orphanet

expertlink

https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=70573

has_age_of_onset

Adult

has_inheritance

Not applicable

hasDbXref

UMLS:C0149925

ICD-10:C34.9

ICD-11:2C25.1

OMIM:182280

MedDRA:10041067

label

Small cell lung cancer

notation

ORPHA:70573

part_of

http://www.orpha.net/ORDO/Orphanet_101945

prefixIRI

ORDO:Orphanet_70573

prefLabel

Small cell lung cancer

present_in

Europe AND has_point_prevalence_average_value : 12.0 AND has_point_prevalence_range : 1-5 / 10 000

treeView

http://www.orpha.net/ORDO/Orphanet_101945

subClassOf

http://www.orpha.net/ORDO/Orphanet_377788

http://www.orpha.net/ORDO/Orphanet_557493

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