Preferred Name |
olanzapine |
|
Synonyms |
olanzapine (Zyprexa) |
|
Definitions |
A synthetic derivative of thienobenzodiazepine with antipsychotic, antinausea, and antiemetic activities. As a selective monoaminergic antagonist, olanzapine binds with high affinity binding to the following receptors: serotoninergic, dopaminergic, muscarinic M1-5, histamine H1, and alpha-1-adrenergic receptors; it binds weakly to gamma-aminobutyric acid type A, benzodiazepine, and beta-adrenergic receptors. The antinausea and antiemetic effects of this agent appear to be due to the blockade of (source : ) |
|
ID |
http://doe-generated-ontology.com/OntoAD#C0171023 |
|
altLabel |
olanzapine (Zyprexa) |
|
contraindicated_drug | ||
definition |
A synthetic derivative of thienobenzodiazepine with antipsychotic, antinausea, and antiemetic activities. As a selective monoaminergic antagonist, olanzapine binds with high affinity binding to the following receptors: serotoninergic, dopaminergic, muscarinic M1-5, histamine H1, and alpha-1-adrenergic receptors; it binds weakly to gamma-aminobutyric acid type A, benzodiazepine, and beta-adrenergic receptors. The antinausea and antiemetic effects of this agent appear to be due to the blockade of (source : ) |
|
hiddenLabel |
Olanzapine Olanzapine |
|
may_treat |
http://doe-generated-ontology.com/OntoAD#C0036341 |
|
prefixIRI |
OntoAD:C0171023 |
|
prefLabel |
Olanzapine olanzapine |
|
subClassOf |
http://doe-generated-ontology.com/OntoAD#C2183343 http://doe-generated-ontology.com/OntoAD#C0003297 http://doe-generated-ontology.com/OntoAD#C1276996 |