Preferred Name |
ventral pancreatic bud |
|
Synonyms |
anterior pancreatic bud ventral pancreatic anlage ventral pancreas anlage anterior pancreatic anlage pancreas primordium ventral bud pancreas ventral primordium duct bud |
|
Definitions |
pancreatic bud that gives rise to the major pancreatic duct. |
|
ID |
http://purl.obolibrary.org/obo/UBERON_0003924 |
|
database_cross_reference |
http://www.snomedbrowser.com/Codes/Details/361437002 http://en.wikipedia.org/wiki/Pancreatic_bud EHDAA2:0001389 EFO:0003464 EMAPA:17256 VHOG:0001429 XAO:0001103 AAO:0011111 ZFA:0001369 TAO:0001369 |
|
definition |
pancreatic bud that gives rise to the major pancreatic duct. |
|
depicted_by |
http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png |
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development_notes |
the ventral pancreas and liver are derived from a common precursor cell population[PMID:16417468]. TODO - add this relationship. The ventral pancreatic bud becomes the head and uncinate process, and comes from the hepatic diverticulum[WP] |
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develops_from | ||
has_exact_synonym |
pancreas primordium ventral bud pancreas ventral primordium duct bud |
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has_obo_namespace |
uberon |
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has_related_synonym |
anterior pancreatic bud ventral pancreatic anlage ventral pancreas anlage anterior pancreatic anlage |
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homology_notes |
In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG] |
|
id |
UBERON:0003924 |
|
imported from | ||
in_subset |
http://purl.obolibrary.org/obo/uberon/core#efo_slim |
|
label |
ventral pancreatic bud |
|
notation |
UBERON:0003924 |
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part_of | ||
prefLabel |
ventral pancreatic bud |
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treeView | ||
subClassOf |