cyclosporin A

A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle.

http://purl.obolibrary.org/obo/CHEBI_4031

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A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle.

C62H111N11O12

http://purl.obolibrary.org/obo/CHEBI_35705

http://purl.obolibrary.org/obo/CHEBI_37153

http://purl.obolibrary.org/obo/CHEBI_149553

http://purl.obolibrary.org/obo/CHEBI_176497

http://purl.obolibrary.org/obo/CHEBI_50903

http://purl.obolibrary.org/obo/CHEBI_25212

http://purl.obolibrary.org/obo/CHEBI_50177

http://purl.obolibrary.org/obo/CHEBI_35718

http://purl.obolibrary.org/obo/CHEBI_35842

http://purl.obolibrary.org/obo/CHEBI_49167

InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1

PMATZTZNYRCHOR-CGLBZJNRSA-N

cyclosporin A

1202.61120

1201.84137

CHEBI:4031

cyclosporin A

CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C

http://purl.obolibrary.org/obo/CHEBI_24613