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Preferred Name

Optic Nerve Glioma
Synonyms

Glioblastoma Multiforme

Malignant Optic Nerve Astrocytoma

Optic Glioma
Definitions

Glial cell derived tumors arising from the optic nerve, usually presenting in childhood. Roughly 50% are associated with NEUROFIBROMATOSIS 1. Clinical manifestations include decreased visual acuity; EXOPHTHALMOS; NYSTAGMUS, PATHOLOGIC; STRABISMUS; pallor or swelling of the optic disc; and INTRACRANIAL HYPERTENSION. The tumor may extend into the optic chiasm and hypothalamus (MeSH).
ID

http://uri.neuinfo.org/nif/nifstd/birnlex_12621
createdDate

2007-10-05
definingCitation

Adams et al., Principles of Neurology, 6th ed, p681
definition

Glial cell derived tumors arising from the optic nerve, usually presenting in childhood. Roughly 50% are associated with NEUROFIBROMATOSIS 1. Clinical manifestations include decreased visual acuity; EXOPHTHALMOS; NYSTAGMUS, PATHOLOGIC; STRABISMUS; pallor or swelling of the optic disc; and INTRACRANIAL HYPERTENSION. The tumor may extend into the optic chiasm and hypothalamus (MeSH).
hasBirnlexCurator

http://uri.neuinfo.org/nif/nifstd/readable/Bill_Bug
hasCurationStatus

http://uri.neuinfo.org/nif/nifstd/readable/uncurated
hasDefinitionSource

http://uri.neuinfo.org/nif/nifstd/readable/MeSH_defSource
hasExternalSource

http://uri.neuinfo.org/nif/nifstd/readable/MeSH
label

Optic Nerve Glioma
MeshUid

D020339
modifiedDate

2007-10-05
preferred label

Optic Nerve Glioma
synonym

Glioblastoma Multiforme

Malignant Optic Nerve Astrocytoma

Optic Glioma
subClassOf

http://purl.obolibrary.org/obo/DOID_0060108

http://uri.neuinfo.org/nif/nifstd/birnlex_12619

http://purl.obolibrary.org/obo/DOID_3069

http://purl.obolibrary.org/obo/DOID_3419
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