loading...| Preferred Name |
Macromolecular complex |
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| Synonyms |
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| Definitions |
A large, multi-molecular biological aggregate held together by van der Waals, hydrophobic, and hydrophilic interactions. Such complexes have a myriad of interactions with other cellular constituents with help to situate them within the cell - e.g., with the periphery of the phospholipid bilayer, penetrating some or all of the bilayer, interactions with intra- or extracellular fibrous matrices, and finally with other macromolecular complexes. Conformational changes in one molecular constituent of a complex frequently caused by covalent modification will tend to high non-local effects on the over conformation and energy profile of all the constituents in the complex. |
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| ID |
http://uri.neuinfo.org/nif/nifstd/birnlex_1 |
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| Obsolete |
true |
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| Contributor |
Bill Bug |
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| createdDate |
2006-09-07 |
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| definition |
A large, multi-molecular biological aggregate held together by van der Waals, hydrophobic, and hydrophilic interactions. Such complexes have a myriad of interactions with other cellular constituents with help to situate them within the cell - e.g., with the periphery of the phospholipid bilayer, penetrating some or all of the bilayer, interactions with intra- or extracellular fibrous matrices, and finally with other macromolecular complexes. Conformational changes in one molecular constituent of a complex frequently caused by covalent modification will tend to high non-local effects on the over conformation and energy profile of all the constituents in the complex. |
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| example |
16S ribosomal complex axonal Na+-K+ ATPase transporter neuronal nicotinic Acetylcholine receptor |
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| label |
Macromolecular complex |
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| owl:deprecated |
true |
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| prefixIRI |
NIFSTD:birnlex_1 |
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| prefLabel |
Macromolecular complex |
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| subClassOf |