loading...| Preferred Name |
Alzheimers disease |
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| Synonyms |
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| Definitions |
an age-related, non-reversible brain disorder that develops over a period of years. Initially, people experience memory loss and confusion, which may be mistaken for the kinds of memory changes that are sometimes associated with normal aging. However, the symptoms of AD gradually lead to behavior and personality changes, a decline in cognitive abilities such as decision-making and language skills, and problems recognizing family and friends. AD ultimately leads to a severe loss of mental function. An amyloidopathy where cognitive deficits [memory, visual spatial, attention, orientation, executive function, functional] occur that represent a decline from previous levels of functioning resulting in dementia caused by neurodegeneration as a result of deposition of amyloid plaques and neurofibrillary tangles in the medial temporal lobes. |
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| ID |
http://purl.obolibrary.org/obo/ND_0000152 |
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| comment |
an age-related, non-reversible brain disorder that develops over a period of years. Initially, people experience memory loss and confusion, which may be mistaken for the kinds of memory changes that are sometimes associated with normal aging. However, the symptoms of AD gradually lead to behavior and personality changes, a decline in cognitive abilities such as decision-making and language skills, and problems recognizing family and friends. AD ultimately leads to a severe loss of mental function. |
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| alternative term |
Alzheimer's disease old-timers' disease Alzheimer disease primary degenerative dementia of the Alzheimers type senile dementia of the Alzheimers type Alzheimer's AD Alzheimers |
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| definition |
An amyloidopathy where cognitive deficits [memory, visual spatial, attention, orientation, executive function, functional] occur that represent a decline from previous levels of functioning resulting in dementia caused by neurodegeneration as a result of deposition of amyloid plaques and neurofibrillary tangles in the medial temporal lobes. |
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| definition editor |
Alexander P. Cox |
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| definition source |
http://www.ninds.nih.gov/disorders/alzheimersdisease/alzheimersdisease.htm |
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| hasDbXref |
http://ontology.neuinfo.org/NIF/Dysfunction/NIF-Dysfunction.owl#birnlex_2092 |
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| label |
Alzheimers disease |
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| prefixIRI |
ND:0000152 |
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| prefLabel |
Alzheimers disease |
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| subClassOf |