loading...| Preferred Name |
Coenzyme Q10 |
|
| Synonyms |
UBIDECARENONE Ubidecarenone 2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecanyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione Ubiquinone 10 coenzyme Q10 Coenzyme Q10 vitamin Q10 Co-Q10 CoQ10 Q10 ubiquinone |
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| Definitions |
A naturally occurring benzoquinone important in electron transport in mitochondrial membranes. Coenzyme Q10 functions as an endogenous antioxidant; deficiencies of this enzyme have been observed in patients with many different types of cancer and limited studies have suggested that coenzyme Q10 may induce tumor regression in patients with breast cancer. This agent may have immunostimulatory effects. (NCI04) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C916 |
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| Accepted_Therapeutic_Use_For |
Chronic heart failure; mitochondrial cytopathies |
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| ALT_DEFINITION |
A nutrient that the body needs in small amounts to function and stay healthy. Coenzyme Q10 helps mitochondria (small structures in the cell) make energy. It is an antioxidant that helps prevent cell damage caused by free radicals (highly reactive chemicals). Coenzyme Q10 is fat-soluble (can dissolve in fats and oils) and is found in fatty fish, beef, soybeans, peanuts, and spinach. It is being studied in the prevention and treatment of some types of cancer and heart disease and in the relief of side effects caused by some cancer treatments. |
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| CAS_Registry |
303-98-0 |
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| CHEBI_ID |
CHEBI:46245 |
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| Chemical_Formula |
C59H90O4 |
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| code |
C916 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
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| Contributing_Source |
CTRP FDA GDC |
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| DEFINITION |
A naturally occurring benzoquinone important in electron transport in mitochondrial membranes. Coenzyme Q10 functions as an endogenous antioxidant; deficiencies of this enzyme have been observed in patients with many different types of cancer and limited studies have suggested that coenzyme Q10 may induce tumor regression in patients with breast cancer. This agent may have immunostimulatory effects. (NCI04) |
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| Display_Name |
Coenzyme Q10 |
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| FDA_UNII_Code |
EJ27X76M46 |
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| FULL_SYN |
UBIDECARENONE Ubidecarenone 2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecanyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione Ubiquinone 10 coenzyme Q10 Coenzyme Q10 vitamin Q10 Co-Q10 CoQ10 Q10 ubiquinone |
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| Is_Value_For_GDC_Property | ||
| label |
Coenzyme Q10 |
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| Legacy Concept Name |
Coenzyme-Q |
|
| Maps_To |
Coenzyme Q10 |
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| NCI_Drug_Dictionary_ID |
39187 |
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| NSC Number |
140865 |
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| PDQ_Closed_Trial_Search_ID |
39187 |
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| PDQ_Open_Trial_Search_ID |
39187 |
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| Preferred_Name |
Coenzyme Q10 |
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| prefixIRI |
Thesaurus:C916 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0056077 |
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| subClassOf |