National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Protease Inhibitor

Synonyms

Protease Inhibitor

Protease Inhibitors

protease inhibitor

Definitions

Any substance that inhibits a protease, an enzyme that breaks peptide bonds. Proteases are required for many cell processes and inhibition of proteases can inhibit viral replication, inflammatory responses, proliferation, and tumor growth.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C783

ALT_DEFINITION

A compound that interferes with the ability of certain enzymes to break down proteins. Some protease inhibitors can keep a virus from making copies of itself (for example, AIDS virus protease inhibitors), and some can prevent cancer cells from spreading.

CHEBI_ID

CHEBI:37670

code

C783

DEFINITION

Any substance that inhibits a protease, an enzyme that breaks peptide bonds. Proteases are required for many cell processes and inhibition of proteases can inhibit viral replication, inflammatory responses, proliferation, and tumor growth.

FULL_SYN

Protease Inhibitor

Protease Inhibitors

protease inhibitor

label

Protease Inhibitor

Legacy Concept Name

Protease_Inhibitor

Preferred_Name

Protease Inhibitor

prefixIRI

Thesaurus:C783

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0033607

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

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http://purl.obolibrary.org/obo/CHEBI_37670 GO-PLUS LOOM
http://purl.obolibrary.org/obo/XCO_0000748 XCO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 OBA LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 CHEBI LOOM
http://www.semanticweb.org/owner/ontologies/2014/6/Drug.owl#ProteaseInhibitor HCODONONT LOOM
http://purl.bioontology.org/ontology/CSP/1040-5919 CRISP LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 BAO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 HUPSON LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 CHIRO LOOM
http://purl.obolibrary.org/obo/CHEBI_37670 MAXO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372528003 SNOMEDCT LOOM
http://doe-generated-ontology.com/OntoAD#C0033607 ONTOAD LOOM
http://purl.obolibrary.org/obo/NCIT_C783 BERO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01941 MIO LOOM
https://bioportal.bioontology.org/ontologies/DMTO.owl#DMTO_0001548 MIDO LOOM
http://purl.jp/bio/4/id/kb0000001642 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/734602008 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10233 OCHV LOOM