Preferred Name |
Methadone |
|
Synonyms |
METHADONE Methadone |
|
Definitions |
A synthetic opioid with analgesic activity. Methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily on the mu-receptor and has actions similar to those of morphine and morphine-like agents. The characteristic morphine-like effects include analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. However, the detoxification symptoms between morphine-like agents and methadone differ in that the onset of methadone's withdrawal symptoms is slower, the course is more prolonged and the symptoms are less severe. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62044 |
|
CAS_Registry |
76-99-3 |
|
CHEBI_ID |
CHEBI:6807 |
|
Chemical_Formula |
C21H27NO |
|
code |
C62044 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
Contributing_Source |
CTRP FDA |
|
DEFINITION |
A synthetic opioid with analgesic activity. Methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily on the mu-receptor and has actions similar to those of morphine and morphine-like agents. The characteristic morphine-like effects include analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. However, the detoxification symptoms between morphine-like agents and methadone differ in that the onset of methadone's withdrawal symptoms is slower, the course is more prolonged and the symptoms are less severe. |
|
Display_Name |
Methadone |
|
FDA_UNII_Code |
UC6VBE7V1Z |
|
FULL_SYN |
METHADONE Methadone |
|
Has_Salt_Form | ||
Has_Target | ||
label |
Methadone |
|
Legacy Concept Name |
Methadone_Base |
|
Preferred_Name |
Methadone |
|
prefixIRI |
Thesaurus:C62044 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0025605 |
|
subClassOf |