loading...| Preferred Name |
Clopidogrel |
|
| Synonyms |
Clopidogrel CLOPIDOGREL |
|
| Definitions |
A thienopyridine, with antiplatelet activity. Clopidogrel targets, irreversibly binds to and alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61686 |
|
| CAS_Registry |
113665-84-2 |
|
| CHEBI_ID |
CHEBI:37941 |
|
| Chemical_Formula |
C16H16ClNO2S |
|
| code |
C61686 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 |
|
| Contributing_Source |
CTRP FDA HemOnc |
|
| DEFINITION |
A thienopyridine, with antiplatelet activity. Clopidogrel targets, irreversibly binds to and alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time. |
|
| Display_Name |
Clopidogrel |
|
| FDA_UNII_Code |
A74586SNO7 |
|
| FULL_SYN |
Clopidogrel CLOPIDOGREL |
|
| Has_Salt_Form | ||
| label |
Clopidogrel |
|
| Legacy Concept Name |
Clopidogrel |
|
| Preferred_Name |
Clopidogrel |
|
| prefixIRI |
Thesaurus:C61686 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0070166 |
|
| subClassOf |