loading...| Preferred Name |
Lidocaine |
|
| Synonyms |
2-Diethylamino-2',6'-acetoxylidide Omega-diethylamino-2,6-dimethylacetanilide .omega.-Diethylamino-2,6-dimethylacetanilide 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide 2-(Diethylamino)-2',6'-acetoxylidide Cuivasil Duncaine LIDOCAINE Leostesin Lidocaine Lidothesin Lignocaine Rucaina lidocaine |
|
| Definitions |
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C614 |
|
| Accepted_Therapeutic_Use_For |
Cardiac arrhythmias; Local anesthetic |
|
| ALT_DEFINITION |
A substance used to relieve pain by blocking signals at the nerve endings in skin. It can also be given intravenously to stop heart arrhythmias. It is a type of local anesthetic and antiarrhythmic. |
|
| CAS_Registry |
137-58-6 |
|
| CHEBI_ID |
CHEBI:6456 |
|
| Chemical_Formula |
C14H22N2O |
|
| code |
C614 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159412 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
|
| Contributing_Source |
CPTAC CTRP FDA |
|
| DEFINITION |
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia. |
|
| Display_Name |
Lidocaine |
|
| FDA_UNII_Code |
98PI200987 |
|
| FULL_SYN |
2-Diethylamino-2',6'-acetoxylidide Omega-diethylamino-2,6-dimethylacetanilide .omega.-Diethylamino-2,6-dimethylacetanilide 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide 2-(Diethylamino)-2',6'-acetoxylidide Cuivasil Duncaine LIDOCAINE Leostesin Lidocaine Lidothesin Lignocaine Rucaina lidocaine |
|
| Has_Salt_Form | ||
| label |
Lidocaine |
|
| Legacy Concept Name |
Lidocaine |
|
| NCI_Drug_Dictionary_ID |
39607 |
|
| NSC Number |
40030 |
|
| PDQ_Closed_Trial_Search_ID |
39607 |
|
| PDQ_Open_Trial_Search_ID |
39607 |
|
| Preferred_Name |
Lidocaine |
|
| prefixIRI |
Thesaurus:C614 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0023660 |
|
| subClassOf |