loading...| Preferred Name |
Triamcinolone Acetonide |
|
| Synonyms |
Triamcinolone Acetonide Aristocort A TRIAMCINOLONE ACETONIDE ReadySharp Triamcinolone 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione AllerNaze Kenalog Nasacort |
|
| Definitions |
The acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48027 |
|
| Accepted_Therapeutic_Use_For |
Allergic Rhinitis |
|
| CAS_Registry |
76-25-5 |
|
| Chemical_Formula |
C24H31FO6 |
|
| code |
C48027 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 |
|
| Contributing_Source |
FDA GDC |
|
| DEFINITION |
The acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. |
|
| FDA_UNII_Code |
F446C597KA |
|
| FULL_SYN |
Triamcinolone Acetonide Aristocort A TRIAMCINOLONE ACETONIDE ReadySharp Triamcinolone 9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione AllerNaze Kenalog Nasacort |
|
| Is_Value_For_GDC_Property | ||
| label |
Triamcinolone Acetonide |
|
| Legacy Concept Name |
Triamcinolone_Acetonide |
|
| Maps_To |
Triamcinolone Acetonide |
|
| NCI_Drug_Dictionary_ID |
649799 |
|
| NSC Number |
21916 |
|
| PDQ_Closed_Trial_Search_ID |
649799 |
|
| PDQ_Open_Trial_Search_ID |
649799 |
|
| Preferred_Name |
Triamcinolone Acetonide |
|
| prefixIRI |
Thesaurus:C48027 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0040866 |
|
| subClassOf |