National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Malignant Neoplasm

Synonyms

Malignant Neoplastic Disease

Neoplasm, malignant

Malignant Tumor

Tumor, malignant, NOS

Malignant Growth

Unclassified tumor, malignant

NEOPLASM, MALIGNANT

Malignant Neoplasm

CA

Cancer

Malignancy

cancer

malignancy

Definitions

A neoplasm composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C9305

ALT_DEFINITION

A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of malignancy. Carcinoma is a malignancy that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a malignancy that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a malignancy that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are malignancies that begin in the cells of the immune system. Central nervous system cancers are malignancies that begin in the tissues of the brain and spinal cord.

A group of diseases in which abnormal cells divide without control, invade nearby tissues and may also spread to other parts of the body through the blood and lymph systems.

Uncontrolled growth of abnormal cells with potential for metastatic spread.

A general term for autonomous tissue growth exhibiting morphologic features of malignancy (e.g. severe atypia, nuclear pleomorphism, tumor cell necrosis, abnormal mitoses, tissue invasiveness) and for which the transformed cell type has not been specifically identified.

code

C9305

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62596

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168661

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168656

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168662

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88025

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156966

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158034

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168658

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156954

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19752

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179027

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189762

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168655

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158520

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156953

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189083

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168657

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99147

Contributing_Source

CDISC

CPTAC

CTRP

FDA

GDC

MedDRA

NICHD

SeroNet

DEFINITION

A neoplasm composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas.

Display_Name

Malignant Neoplasm

FULL_SYN

Malignant Neoplastic Disease

Neoplasm, malignant

Malignant Tumor

Tumor, malignant, NOS

Malignant Growth

Unclassified tumor, malignant

NEOPLASM, MALIGNANT

Malignant Neoplasm

CA

Cancer

Malignancy

cancer

malignancy

ICD-O-3_Code

8000/3

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177621

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17103

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C178243

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176985

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16457

label

Malignant Neoplasm

Legacy Concept Name

Malignant_Neoplasm

Maps_To

Malignant neoplasm of other and ill-defined sites: Lower limb

Neoplasm, malignant

Malignant neoplasm, primary site unknown, so stated

Tumor, malignant, NOS

Other malignant neoplasm of unspecified site

Malignant neoplasm of other and ill-defined sites

Unclassified tumor, malignant

Malignant neoplasm, without specification of site

Malignant neoplasm, unspecified

Malignant neoplasm of other specified sites

Malignant neoplasm of other and ill-defined sites: Overlapping lesion of other and ill-defined sites

Malignant neoplasm without specification of site

8000/3

Cancer

Malignancy

Neoplastic_Status

Malignant

Preferred_Name

Malignant Neoplasm

prefixIRI

Thesaurus:C9305

Semantic_Type

Neoplastic Process

UMLS_CUI

C1861853

xRef

IMDRF:E1801

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7062

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