loading...| Preferred Name |
Mycophenolate Sodium |
|
| Synonyms |
Socium Mycophenolate Mycophenolate Sodium MYCOPHENOLATE SODIUM 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, monosodium salt, (4E)- ERL 080 ERL 080A |
|
| Definitions |
The sodium salt form of mycophenolic acid (MPA), with immunosuppressing activity. In vivo, the active molecule MPA reversibly inhibits inosine monophosphate dehydrogenase (IMPDH) which is needed for guanine monophosphate synthesis and stops the proliferation of B and T lymphocytes. Relative to other cell types, lypmocytes are highly dependent on salvage and de novo synthesis of guanine nucleotides, thus making these cells prone to MPA cytotoxicity. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66215 |
|
| CAS_Registry |
37415-62-6 |
|
| Chemical_Formula |
C17H19O6.Na |
|
| code |
C66215 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The sodium salt form of mycophenolic acid (MPA), with immunosuppressing activity. In vivo, the active molecule MPA reversibly inhibits inosine monophosphate dehydrogenase (IMPDH) which is needed for guanine monophosphate synthesis and stops the proliferation of B and T lymphocytes. Relative to other cell types, lypmocytes are highly dependent on salvage and de novo synthesis of guanine nucleotides, thus making these cells prone to MPA cytotoxicity. |
|
| FDA_UNII_Code |
WX877SQI1G |
|
| FULL_SYN |
Socium Mycophenolate Mycophenolate Sodium MYCOPHENOLATE SODIUM 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, monosodium salt, (4E)- ERL 080 ERL 080A |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Mycophenolate Sodium |
|
| Legacy Concept Name |
Mycophenolate_Sodium |
|
| NSC Number |
116072 |
|
| Preferred_Name |
Mycophenolate Sodium |
|
| prefixIRI |
Thesaurus:C66215 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C1337395 |
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| subClassOf |