loading...| Preferred Name |
Inosine Monophosphate Dehydrogenase Inhibitor |
|
| Synonyms |
Inosine Monophosphate Dehydrogenase Inhibitor Inosine 5'-Phosphate Dehydrogenase Inhibitor IMPDH Inhibitors |
|
| Definitions |
Any substance that inhibits inosine monophosphate dehydrogenase, an enzyme that catalyzes the conversion of inosine monophosphate to xanthosine monophosphate, the rate-limiting step in the de novo biosynthesis of guanine nucleotides. Inhibition of inosine monophosphate dehydrogenase can lead to inhibition of cell proliferation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2087 |
|
| CHEBI_ID |
CHEBI:53746 |
|
| code |
C2087 |
|
| DEFINITION |
Any substance that inhibits inosine monophosphate dehydrogenase, an enzyme that catalyzes the conversion of inosine monophosphate to xanthosine monophosphate, the rate-limiting step in the de novo biosynthesis of guanine nucleotides. Inhibition of inosine monophosphate dehydrogenase can lead to inhibition of cell proliferation. |
|
| FULL_SYN |
Inosine Monophosphate Dehydrogenase Inhibitor Inosine 5'-Phosphate Dehydrogenase Inhibitor IMPDH Inhibitors |
|
| label |
Inosine Monophosphate Dehydrogenase Inhibitor |
|
| Legacy Concept Name |
Inosine_Monophosphate_Dehydrogenase_Inhibitor |
|
| Preferred_Name |
Inosine Monophosphate Dehydrogenase Inhibitor |
|
| prefixIRI |
Thesaurus:C2087 |
|
| Semantic_Type |
Chemical Viewed Functionally |
|
| UMLS_CUI |
C1512792 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/NCIT_C2087 | BERO | LOOM | |
| http://purl.obolibrary.org/obo/CHEBI_53746 | DINTO | LOOM | |
| http://purl.obolibrary.org/obo/CHEBI_53746 | BIOMODELS | LOOM | |
| http://purl.obolibrary.org/obo/CHEBI_53746 | CHIRO | LOOM |