National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Esophageal Perforation

Synonyms

Esophageal perforation

Esophageal Perforation

Perforation of Esophagus

Perforation Of Esophagus

Definitions

The presence of a hole or other type of opening in the esophageal wall through which the contents of the esophagus can pass into the mediastinum. The most common cause of esophageal perforation is injury during a medical procedure such as esophagoscopy or placement of a naso-gastric tube; and pathologic process such as neoplasm or gastric reflux with ulceration. Less common causes include injuries from penetrating or blunt trauma or injury to the esophagus during an operation on another organ, mechanical problem such as violent retching or vomiting; ingestion of a foreign body or caustic agents. The condition often results in infection of the mediastinum and mediastinitis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C50693

ALT_DEFINITION

The presence of a hole or other type of opening in the esophageal wall through which the contents of the esophagus can pass into the mediastinum.

A disorder characterized by a rupture in the wall of the esophagus.

code

C50693

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62596

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99147

Contributing_Source

CTCAE

FDA

NICHD

DEFINITION

The presence of a hole or other type of opening in the esophageal wall through which the contents of the esophagus can pass into the mediastinum. The most common cause of esophageal perforation is injury during a medical procedure such as esophagoscopy or placement of a naso-gastric tube; and pathologic process such as neoplasm or gastric reflux with ulceration. Less common causes include injuries from penetrating or blunt trauma or injury to the esophagus during an operation on another organ, mechanical problem such as violent retching or vomiting; ingestion of a foreign body or caustic agents. The condition often results in infection of the mediastinum and mediastinitis.

FDA_Table

Patient Code (Appendix B)

FULL_SYN

Esophageal perforation

Esophageal Perforation

Perforation of Esophagus

Perforation Of Esophagus

label

Esophageal Perforation

Legacy Concept Name

Perforation_Of_Esophagus

Preferred_Name

Esophageal Perforation

prefixIRI

Thesaurus:C50693

Semantic_Type

Finding

UMLS_CUI

C0014860

xRef

IMDRF:E1022

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C79470

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35328

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