loading...| Preferred Name |
Primary Hyperparathyroidism |
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| Synonyms |
Primary Hyperparathyroidism |
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| Definitions |
Hyperfunction of the parathyroid glands resulting in the overproduction of parathyroid hormone. It is caused by parathyroid adenoma, parathyroid hyperplasia, parathyroid carcinoma, and multiple endocrine neoplasia. It is associated with hypercalcemia and hypophosphatemia. Signs and symptoms include weakness, fatigue, nausea, vomiting, constipation, depression, bone pain, osteoporosis, cystic bone lesions, and kidney stones. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C48280 |
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| ALT_DEFINITION |
Hyperparathyroidism due to a condition originating within the parathyroid glands, resulting in hypercalcemia due to increased release of calcium and phosphate from bone matrix, increased renal calcium reabsorption, and increased renal production of 1,25-dihydroxyvitamin D, which increases intestinal absorption of calcium. Primary hyperparathyroidism is also associated with hypophosphatemia as a result of phosphaturia. Clinical features include weakness, fatigue, nausea, vomiting, constipation, depression, and, if chronic, bone pain, osteoporosis, cystic bone lesions, and kidney stones. |
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| code |
C48280 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118467 |
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| Contributing_Source |
MedDRA NICHD |
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| DEFINITION |
Hyperfunction of the parathyroid glands resulting in the overproduction of parathyroid hormone. It is caused by parathyroid adenoma, parathyroid hyperplasia, parathyroid carcinoma, and multiple endocrine neoplasia. It is associated with hypercalcemia and hypophosphatemia. Signs and symptoms include weakness, fatigue, nausea, vomiting, constipation, depression, bone pain, osteoporosis, cystic bone lesions, and kidney stones. |
|
| FULL_SYN |
Primary Hyperparathyroidism |
|
| label |
Primary Hyperparathyroidism |
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| Legacy Concept Name |
Primary_Hyperparathyroidism |
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| Maps_To |
Primary hyperparathyroidism |
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| Preferred_Name |
Primary Hyperparathyroidism |
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| prefixIRI |
Thesaurus:C48280 |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0221002 |
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| subClassOf |