loading...| Preferred Name |
Toxic Shock Syndrome |
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| Synonyms |
Toxic Shock Syndrome TSS |
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| Definitions |
A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C35498 |
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| ALT_DEFINITION |
A rare acute life-threatening systemic bacterial noncontagious illness caused by staphylococcal exotoxins. Profoundly reduced blood flow that results in impaired tissue perfusion and possible end organ damage resulting from an exotoxin released from certain bacteria, most often Staphylococcus aureus, or Streptococcus pyogenes. |
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| code |
C35498 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62596 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128453 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54450 |
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| Contributing_Source |
FDA MedDRA NICHD |
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| DEFINITION |
A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria. |
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| FDA_Table |
Patient Code (Appendix B) |
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| FULL_SYN |
Toxic Shock Syndrome TSS |
|
| label |
Toxic Shock Syndrome |
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| Legacy Concept Name |
Toxic_Shock_Syndrome |
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| Maps_To |
Toxic shock syndrome |
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| Preferred_Name |
Toxic Shock Syndrome |
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| prefixIRI |
Thesaurus:C35498 |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0600327 |
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| xRef |
IMDRF:E1414 |
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| subClassOf |