loading...| Preferred Name |
Cushing Syndrome |
|
| Synonyms |
Cortisol Excess Cushing syndrome Cushing's Syndrome Hypercortisolism Cushing Syndrome |
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| Definitions |
A syndrome caused by high levels of cortisol in the blood either due to excessive production and secretion of corticosteroids secondary to pituitary or adrenocortical neoplasms, or intake of glucocorticoid drugs. Signs and symptoms include a round face, upper body obesity, fragile and thin skin, purple stretch marks in the skin, fatigue, muscle weakness, hypertension, diabetes mellitus, hypertrichosis and amenorrhea in women, impotence in men, and osteoporosis. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2969 |
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| ALT_DEFINITION |
A clinical condition characterized by variable degrees of central obesity, rounding of the face ("moon" face), hypertension, striae, and a number of other physical findings, as a result of prolonged exposure to supranormal cortisol concentration of any etiology. A condition in which there is too much cortisol (a hormone made by the outer layer of the adrenal gland) in the body. Cushing syndrome may be caused by taking too many steroid drugs or by certain types of tumors. Tumors that make adrenocorticotropic hormone (ACTH) cause the adrenal gland to make too much cortisol. Symptoms of Cushing syndrome include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure, high blood sugar, purple or pink stretch marks on the skin, and weight gain, especially in the abdomen. |
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| code |
C2969 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186315 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118467 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189762 |
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| Contributing_Source |
MedDRA NICHD PCDC |
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| DEFINITION |
A syndrome caused by high levels of cortisol in the blood either due to excessive production and secretion of corticosteroids secondary to pituitary or adrenocortical neoplasms, or intake of glucocorticoid drugs. Signs and symptoms include a round face, upper body obesity, fragile and thin skin, purple stretch marks in the skin, fatigue, muscle weakness, hypertension, diabetes mellitus, hypertrichosis and amenorrhea in women, impotence in men, and osteoporosis. |
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| FULL_SYN |
Cortisol Excess Cushing syndrome Cushing's Syndrome Hypercortisolism Cushing Syndrome |
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| label |
Cushing Syndrome |
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| Legacy Concept Name |
Cushing_s_Syndrome |
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| Maps_To |
Cushing's syndrome |
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| Preferred_Name |
Cushing Syndrome |
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| prefixIRI |
Thesaurus:C2969 |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0010481 |
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| subClassOf |