loading...| Preferred Name |
eptifibatide |
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| Synonyms |
L-Cysteinamide cyclic(1-6)-disulfide N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl- L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic(1-6)-disulfide integrilin |
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| Definitions |
A cyclical heptapeptide with anticoagulant activity. Eptifibatide selectively and reversibly binds to and blocks the platelet glycoprotein IIb/IIIa receptor. This prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands and leads to an inhibition of platelet aggregation and prevents thrombus development. [url:http://purl.obolibrary.org/obo/NCIT_C47516] |
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| ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02157 |
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| definition |
A cyclical heptapeptide with anticoagulant activity. Eptifibatide selectively and reversibly binds to and blocks the platelet glycoprotein IIb/IIIa receptor. This prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands and leads to an inhibition of platelet aggregation and prevents thrombus development. [url:http://purl.obolibrary.org/obo/NCIT_C47516] |
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| label |
eptifibatide |
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| MIO_ID |
MIO:02157 |
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| prefLabel |
eptifibatide |
|
| reference |
UMLS:C0253563 CHEBI:291902 NCIT:C47516 |
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| synonyms |
L-Cysteinamide cyclic(1-6)-disulfide N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl- L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic(1-6)-disulfide integrilin |
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| subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02155 http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01097 |