Myocardial Infarction Ontology

Last uploaded: February 21, 2023
Preferred Name

glycoprotein IIb/IIIa antagonist

Synonyms

GpIIb/IIIa inhibitors

GPIIb/IIa antagonist

glycoprotein IIb/IIIa inhibitor

glycoprotein IIb/IIIa inhibitors

Definitions

A class of agents that act by selectively inhibiting glycoprotein IIb/IIIa with anticoagulant activity. Glycoprotein IIb/IIIa antagonists bind to and block the activation of the platelet-surface integrin glycoprotein IIb/IIIa, thus preventing the binding of fibrinogen and von Willebrand factor leading to the inhibition of platelet activation and aggregation. [url:http://purl.obolibrary.org/obo/NCIT_C101256]

ID

http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02155

definition

A class of agents that act by selectively inhibiting glycoprotein IIb/IIIa with anticoagulant activity. Glycoprotein IIb/IIIa antagonists bind to and block the activation of the platelet-surface integrin glycoprotein IIb/IIIa, thus preventing the binding of fibrinogen and von Willebrand factor leading to the inhibition of platelet activation and aggregation. [url:http://purl.obolibrary.org/obo/NCIT_C101256]

label

glycoprotein IIb/IIIa antagonist

MIO_ID

MIO:02155

prefLabel

glycoprotein IIb/IIIa antagonist

reference

NCIT:C101256

UMLS:C3640054

synonyms

GpIIb/IIIa inhibitors

GPIIb/IIa antagonist

glycoprotein IIb/IIIa inhibitor

glycoprotein IIb/IIIa inhibitors

subClassOf

http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01097

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