loading...| Preferred Name |
eplerenone |
|
| Synonyms |
9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester inspra |
|
| Definitions |
A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerenone is used in the treatment of hypertension and congestive heart failure. [url:http://purl.obolibrary.org/obo/NCIT_C47513] |
|
| ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02118 |
|
| definition |
A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerenone is used in the treatment of hypertension and congestive heart failure. [url:http://purl.obolibrary.org/obo/NCIT_C47513] |
|
| label |
eplerenone |
|
| MIO_ID |
MIO:02118 |
|
| prefLabel |
eplerenone |
|
| reference |
CHEBI:31547 NCIT:C47513 UMLS:C0961485 |
|
| synonyms |
9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester inspra |
|
| subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01066 |