Preferred Name |
aldosterone |
|
Synonyms |
(+)-Aldosterone |
|
Definitions |
A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to mineralocorticoid receptors (MR; NR3C2) and MR-aldosterone complexes regulate the expression of genes involved in the retention of sodium, the secretion of potassium, and water reabsorption, all of which may result increased blood pressure. [url:http://purl.obolibrary.org/obo/NCIT_C219] |
|
ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01413 |
|
definition |
A mineralocorticoid hormone produced by aldosterone synthase (CYP11B2) in the zona glomerulosa of the adrenal cortex. Aldosterone binds to mineralocorticoid receptors (MR; NR3C2) and MR-aldosterone complexes regulate the expression of genes involved in the retention of sodium, the secretion of potassium, and water reabsorption, all of which may result increased blood pressure. [url:http://purl.obolibrary.org/obo/NCIT_C219] |
|
label |
aldosterone |
|
MIO_ID |
MIO:01413 |
|
prefLabel |
aldosterone |
|
reference |
NCIT:C219 |
|
synonyms |
(+)-Aldosterone |
|
subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02387 http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00715 |