Preferred Name |
clopidogrel |
|
Synonyms |
clopidogrel bisulfate Plavix |
|
Definitions |
A thienopyridine, with antiplatelet activity. Clopidogrel targets, irreversibly binds to and alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time. [url:http://purl.obolibrary.org/obo/NCIT_C61686] |
|
ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01069 |
|
definition |
A thienopyridine, with antiplatelet activity. Clopidogrel targets, irreversibly binds to and alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time. [url:http://purl.obolibrary.org/obo/NCIT_C61686] |
|
label |
clopidogrel |
|
MIO_ID |
MIO:01069 |
|
prefLabel |
clopidogrel |
|
reference |
NCIT:C61686 |
|
synonyms |
clopidogrel bisulfate Plavix |
|
subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02641 http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00523 http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00524 |