Medical Subject Headings

Last uploaded: January 31, 2024

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Preferred Name	Pentoxifylline
Synonyms	BL191 Agapurin BL-191 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)- Trental Oxpentifylline BL 191 Torental Pentoxil
Definitions	A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
ID	http://purl.bioontology.org/ontology/MESH/D010431
altLabel	BL191 Agapurin BL-191 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)- Trental Oxpentifylline BL 191 Torental Pentoxil
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0729163 C0699487 C0699489 C0699488 C1256382 C0030899
DC	1
definition	A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
DX	19910101
HN	91(77)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	SD6QCT3TSU 0
isa	http://purl.bioontology.org/ontology/MESH/D016166 http://purl.bioontology.org/ontology/MESH/D010975 http://purl.bioontology.org/ontology/MESH/D011837 http://purl.bioontology.org/ontology/MESH/D014665 http://purl.bioontology.org/ontology/MESH/D010726
LT	TRD
Machine permutation	91; see THEOBROMINE 1977-90
Mapped from	http://purl.bioontology.org/ontology/MESH/C061298 http://purl.bioontology.org/ontology/MESH/C442144 http://purl.bioontology.org/ontology/MESH/C442143 http://purl.bioontology.org/ontology/MESH/C025189 http://purl.bioontology.org/ontology/MESH/C047155 http://purl.bioontology.org/ontology/MESH/C047154 http://purl.bioontology.org/ontology/MESH/C559761 http://purl.bioontology.org/ontology/MESH/C062028 http://purl.bioontology.org/ontology/MESH/C047187 http://purl.bioontology.org/ontology/MESH/C111875 http://purl.bioontology.org/ontology/MESH/C000626018
MDA	19760416
MMR	20160531
MN	D03.633.100.759.758.824.651.700
notation	D010431
PA	D010975 D011837 D016166 D010726 D014665
prefLabel	Pentoxifylline
RR	6493-05-6 (Pentoxifylline)
TERMUI	T030825 T030822 T030820 T030824 T030823 T030821 T748995
TH	USAN (1976) NLM (1990) FDA SRS (2014) UNK (19XX) INN (19XX) NLM (2010) USP (19XX) BAN (19XX)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D013805

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/SNMI/C-A7210	SNMI	CUI
http://purl.bioontology.org/ontology/RCD/x02t8	RCD	CUI
http://purl.bioontology.org/ontology/CSP/4006-0076	CRISP	CUI
http://purl.bioontology.org/ontology/CSP/4006-0076	CRISP	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041432	PDQ	CUI
http://purl.bioontology.org/ontology/SNMI/C-C2798	SNMI	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387522004	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/LNC/MTHU035938	LOINC	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000041432	PDQ	CUI
http://purl.bioontology.org/ontology/SNMI/C-A7210	SNMI	CUI
http://purl.bioontology.org/ontology/LNC/LP14918-4	LOINC	CUI
http://purl.bioontology.org/ontology/ATC/C04AD03	ATC	CUI
http://purl.bioontology.org/ontology/MSHFRE/D010431	MSHFRE	CUI
http://purl.bioontology.org/ontology/SCTSPA/91376007	SCTSPA	CUI
http://purl.bioontology.org/ontology/LNC/LP269085-9	LOINC	CUI
http://purl.bioontology.org/ontology/RXNORM/8013	RXNORM	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/91376007	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000005749	NDFRT	CUI
http://purl.bioontology.org/ontology/VANDF/4018468	VANDF	CUI
http://purl.bioontology.org/ontology/NDDF/002098	NDDF	CUI
http://purl.bioontology.org/ontology/SCTSPA/387522004	SCTSPA	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146791	NDFRT	CUI
http://purl.bioontology.org/ontology/LNC/MTHU002178	LOINC	CUI
http://purl.bioontology.org/ontology/RCD/bn4..	RCD	CUI
http://purl.obolibrary.org/obo/XCO_0001204	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7986	CHEBI	LOOM
http://purl.obolibrary.org/obo/XCO_0001204	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7986	CHEBI	LOOM
http://purl.bioontology.org/ontology/CSP/4006-0076	CRISP	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387522004	SNOMEDCT	LOOM
http://purl.obolibrary.org/obo/CHEBI_7986	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7986	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7986	DRON	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU035938	LOINC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9447	OCHV	LOOM
http://purl.obolibrary.org/obo/OMIT_0011425	OMIT	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000041432	PDQ	LOOM
http://purl.obolibrary.org/obo/dinto_DB00806	DINTO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017863	PMAPP-PMO	LOOM
https://go.drugbank.com/drugs/DB00806	MDM	LOOM
http://purl.bioontology.org/ontology/SNMI/C-A7210	SNMI	LOOM
http://purl.bioontology.org/ontology/LNC/LP14918-4	LOINC	LOOM
http://purl.bioontology.org/ontology/ATC/C04AD03	ATC	LOOM
http://purl.obolibrary.org/obo/MESH_D010431	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010431	RH-MESH	LOOM
http://purl.bioontology.org/ontology/RXNORM/8013	RXNORM	LOOM
http://stirdf.jst.go.jp/id/200907035146649783	IOBC	LOOM
http://purl.bioontology.org/ontology/VANDF/4018468	VANDF	LOOM
http://purl.bioontology.org/ontology/NDDF/002098	NDDF	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C733	NCIT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0030899	OCHV	LOOM
http://purl.obolibrary.org/obo/NCIT_C733	BERO	LOOM
http://www.drugbank.ca/drugs/DB00806	FTC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146791	NDFRT	LOOM
http://purl.jp/bio/4/id/200906055042872488	IOBC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.759.758.824.651.700	RH-MESH	LOOM