loading...| Preferred Name |
Acetazolamide |
|
| Synonyms |
Diamox |
|
| Definitions |
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000086 |
|
| altLabel |
Diamox Acetadiazol Acetazolam Diuramide Apo Acetazolamide Ak Zol Huma Zolamide Acetazolamide, Monosodium Salt Ak-Zol AkZol Acetazolamide Sodium, (Sterile) Edemox ApoAcetazolamide Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)- Huma-Zolamide Glaupax Apo-Acetazolamide HumaZolamide Défiltran Glauconox Diacarb |
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C1448327 C1448330 C1448326 C0949206 C1448328 C1448325 C1448329 C0699249 C0000981 C1448331 C0282036 C1448332 C0591362 C1448333 C0699248 |
|
| DC |
1 |
|
| definition |
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) |
|
| DX |
19660101 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
O3FX965V0I 1424-27-7 0 |
|
| isa |
http://purl.bioontology.org/ontology/MESH/D000927 |
|
| LT |
TRD |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C030084 http://purl.bioontology.org/ontology/MESH/C446053 http://purl.bioontology.org/ontology/MESH/C053646 |
|
| MDA |
19990101 |
|
| MMR |
20160624 |
|
| MN |
D03.383.129.708.867.060 D02.886.675.867.060 |
|
| notation |
D000086 |
|
| PA |
D000927 D004232 D002257 |
|
| prefLabel |
Acetazolamide |
|
| RR |
1424-27-7 (mono-Na salt) 59-66-5 (Acetazolamide) |
|
| TERMUI |
T505100 T000237 T505116 T505096 T000234 T000235 T505144 T360880 T505106 T505098 T000236 T505108 T000238 T505113 T505095 |
|
| TH |
US MX UK NL NLM (1999) CA FDA SRS (2014) ES UNK (19XX) INN (19XX) DE AU USP (19XX) BAN (19XX) FR IE |
|
| tui |
T109 T121 |
|
| subClassOf |