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Last uploaded: August 28, 2024

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Preferred Name	Tamoxifen
Synonyms	Citrate, Tamoxifen ICI 46,474 ICI46474 ICI 47699 Tamoxifen Citrate ICI46,474 Soltamox ICI-46474 Tomaxithen Novaldex Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)- Nolvadex ICI47699 Zitazonium ICI-46,474 ICI-47699 ICI 46474
Definitions	One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
ID	http://purl.bioontology.org/ontology/MESH/D013629
altLabel	Citrate, Tamoxifen ICI 46,474 ICI46474 ICI 47699 Tamoxifen Citrate ICI46,474 Soltamox ICI-46474 Tomaxithen Novaldex Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)- Nolvadex ICI47699 Zitazonium ICI-46,474 ICI-47699 ICI 46474
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0919390 C0086442 C0079589 C0039286 C0700621 C0205958 C0043508 C1515205
DC	1
definition	One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
DX	19780101
HN	78(75); was see under STILBENES 1975-77
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	7FRV7310N6 094ZI81Y45 0
isa	http://purl.bioontology.org/ontology/MESH/D020845 http://purl.bioontology.org/ontology/MESH/D004965 http://purl.bioontology.org/ontology/MESH/D050071 http://purl.bioontology.org/ontology/MESH/D018931
LT	TRD
Machine permutation	78; was see under STILBENES 1975-77
Mapped from	http://purl.bioontology.org/ontology/MESH/C119993 http://purl.bioontology.org/ontology/MESH/C487556 http://purl.bioontology.org/ontology/MESH/C487555 http://purl.bioontology.org/ontology/MESH/C102002 http://purl.bioontology.org/ontology/MESH/C119141 http://purl.bioontology.org/ontology/MESH/C403901 http://purl.bioontology.org/ontology/MESH/C454061 http://purl.bioontology.org/ontology/MESH/C535542 http://purl.bioontology.org/ontology/MESH/C087492 http://purl.bioontology.org/ontology/MESH/C035092 http://purl.bioontology.org/ontology/MESH/C058696 http://purl.bioontology.org/ontology/MESH/C583041 http://purl.bioontology.org/ontology/MESH/C091454 http://purl.bioontology.org/ontology/MESH/C055492 http://purl.bioontology.org/ontology/MESH/C070665 http://purl.bioontology.org/ontology/MESH/C105595 http://purl.bioontology.org/ontology/MESH/C064590 http://purl.bioontology.org/ontology/MESH/C035930 http://purl.bioontology.org/ontology/MESH/C049433 http://purl.bioontology.org/ontology/MESH/C045973 http://purl.bioontology.org/ontology/MESH/C066463 http://purl.bioontology.org/ontology/MESH/C071362 http://purl.bioontology.org/ontology/MESH/C068941 http://purl.bioontology.org/ontology/MESH/C031860 http://purl.bioontology.org/ontology/MESH/C000608205 http://purl.bioontology.org/ontology/MESH/C035830 http://purl.bioontology.org/ontology/MESH/C449941 http://purl.bioontology.org/ontology/MESH/C044549 http://purl.bioontology.org/ontology/MESH/C039305 http://purl.bioontology.org/ontology/MESH/C528171 http://purl.bioontology.org/ontology/MESH/C101859 http://purl.bioontology.org/ontology/MESH/C081654 http://purl.bioontology.org/ontology/MESH/C408984 http://purl.bioontology.org/ontology/MESH/C078476 http://purl.bioontology.org/ontology/MESH/C078477 http://purl.bioontology.org/ontology/MESH/C047288 http://purl.bioontology.org/ontology/MESH/C000590551 http://purl.bioontology.org/ontology/MESH/C064635 http://purl.bioontology.org/ontology/MESH/C037727 http://purl.bioontology.org/ontology/MESH/C037728 http://purl.bioontology.org/ontology/MESH/C037726 http://purl.bioontology.org/ontology/MESH/C050572 http://purl.bioontology.org/ontology/MESH/C028787 http://purl.bioontology.org/ontology/MESH/C049603 http://purl.bioontology.org/ontology/MESH/C049602 http://purl.bioontology.org/ontology/MESH/C049601 http://purl.bioontology.org/ontology/MESH/C118314 http://purl.bioontology.org/ontology/MESH/C035360 http://purl.bioontology.org/ontology/MESH/C518883 http://purl.bioontology.org/ontology/MESH/C000626562 http://purl.bioontology.org/ontology/MESH/C038345 http://purl.bioontology.org/ontology/MESH/C064002 http://purl.bioontology.org/ontology/MESH/C040745 http://purl.bioontology.org/ontology/MESH/C047588 http://purl.bioontology.org/ontology/MESH/C055856 http://purl.bioontology.org/ontology/MESH/C062264 http://purl.bioontology.org/ontology/MESH/C062262 http://purl.bioontology.org/ontology/MESH/C064400 http://purl.bioontology.org/ontology/MESH/C035174 http://purl.bioontology.org/ontology/MESH/C035179 http://purl.bioontology.org/ontology/MESH/C050334 http://purl.bioontology.org/ontology/MESH/C051155 http://purl.bioontology.org/ontology/MESH/C075421 http://purl.bioontology.org/ontology/MESH/C050440 http://purl.bioontology.org/ontology/MESH/C110902 http://purl.bioontology.org/ontology/MESH/C031859 http://purl.bioontology.org/ontology/MESH/C055269 http://purl.bioontology.org/ontology/MESH/C122072 http://purl.bioontology.org/ontology/MESH/C585070 http://purl.bioontology.org/ontology/MESH/C520103 http://purl.bioontology.org/ontology/MESH/C105081 http://purl.bioontology.org/ontology/MESH/C105082 http://purl.bioontology.org/ontology/MESH/C105080 http://purl.bioontology.org/ontology/MESH/C105083 http://purl.bioontology.org/ontology/MESH/C053812 http://purl.bioontology.org/ontology/MESH/C067536 http://purl.bioontology.org/ontology/MESH/C532124 http://purl.bioontology.org/ontology/MESH/C110618 http://purl.bioontology.org/ontology/MESH/C413703 http://purl.bioontology.org/ontology/MESH/C035929 http://purl.bioontology.org/ontology/MESH/C406026 http://purl.bioontology.org/ontology/MESH/C016601 http://purl.bioontology.org/ontology/MESH/C571818 http://purl.bioontology.org/ontology/MESH/C064397 http://purl.bioontology.org/ontology/MESH/C064398 http://purl.bioontology.org/ontology/MESH/C052626 http://purl.bioontology.org/ontology/MESH/C047993 http://purl.bioontology.org/ontology/MESH/C404884 http://purl.bioontology.org/ontology/MESH/C404883 http://purl.bioontology.org/ontology/MESH/C574385
MDA	19741111
MMR	20160701
MN	D02.455.426.559.389.150.700.900
notation	D013629
PA	D050071 D018931 D004965 D020845
prefLabel	Tamoxifen
RR	10540-29-1 (Tamoxifen) 54965-24-1 (citrate) 7FRV7310N6
TERMUI	T040033 T667831 T040035 T040032 T040038 T040034 T040039 T040037 T040036 T040040
TH	USAN (1976) FDA SRS (2014) NLM (1978) UNK (19XX) INN (19XX) NLM (2007) USP (19XX) BAN (19XX)
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D013267

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/CSP/0119-1179	CRISP	CUI
http://purl.bioontology.org/ontology/MSHFRE/D013629	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNMI/C-781E1	SNMI	CUI
http://purl.bioontology.org/ontology/SNMI/C-781E0	SNMI	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042901	PDQ	CUI
http://purl.bioontology.org/ontology/RXNORM/498464	RXNORM	CUI
http://purl.bioontology.org/ontology/RCD/x02l4	RCD	CUI
http://purl.bioontology.org/ontology/RXNORM/281964	RXNORM	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000179289	NDFRT	CUI
http://purl.bioontology.org/ontology/NDDF/002670	NDDF	CUI
http://purl.bioontology.org/ontology/RXNORM/40137	RXNORM	CUI
http://purl.bioontology.org/ontology/SCTSPA/41395001	SCTSPA	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042901	PDQ	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146786	NDFRT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/41395001	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/VANDF/4018462	VANDF	CUI
http://purl.bioontology.org/ontology/MSHFRE/D013629	MSHFRE	CUI
http://purl.bioontology.org/ontology/RXNORM/10324	RXNORM	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/373345002	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/NDDF/004826	NDDF	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007041	NDFRT	CUI
http://purl.bioontology.org/ontology/ATC/L02BA01	ATC	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/75959001	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/LNC/LA14344-8	LOINC	CUI
http://purl.bioontology.org/ontology/CSP/0119-1179	CRISP	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042901	PDQ	CUI
http://purl.bioontology.org/ontology/LNC/MTHU003102	LOINC	CUI
http://purl.bioontology.org/ontology/SCTSPA/373345002	SCTSPA	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000148024	NDFRT	CUI
http://purl.bioontology.org/ontology/SCTSPA/75959001	SCTSPA	CUI
http://purl.bioontology.org/ontology/LNC/LP18484-3	LOINC	CUI
http://purl.bioontology.org/ontology/RCD/he4..	RCD	CUI
http://purl.bioontology.org/ontology/VANDF/4019939	VANDF	CUI
http://purl.bioontology.org/ontology/MSHFRE/D013629	MSHFRE	CUI
http://purl.bioontology.org/ontology/MSHFRE/D013629	MSHFRE	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042901	PDQ	CUI
http://purl.obolibrary.org/obo/CHEBI_41774	OBA	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	EFO	LOOM
http://purl.bioontology.org/ontology/SNMI/C-781E0	SNMI	LOOM
http://purl.bioontology.org/ontology/RXNORM/10324	NLMVS	LOOM
http://purl.bioontology.org/ontology/RXNORM/10324	RXNORM	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016780	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013629	RH-MESH	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	INBANCIDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	HOIP	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	DINTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	COVID-19	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	FYPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	TXPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	CIDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	HINO	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_41774	ODNAE	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62078	NCIT	LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_41774	NPO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373345002	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/NDDF/004826	NDDF	LOOM
http://purl.obolibrary.org/obo/MESH_D013629	BERO	LOOM
http://stirdf.jst.go.jp/id/200907076113483543	IOBC	LOOM
http://purl.bioontology.org/ontology/ATC/L02BA01	ATC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0039286	OCHV	LOOM
http://purl.bioontology.org/ontology/LNC/LA14344-8	LOINC	LOOM
http://www.drugbank.ca/drugs/DB00675	FTC	LOOM
http://purl.bioontology.org/ontology/CSP/0119-1179	CRISP	LOOM
http://www.bioontology.org/pma.owl#PMA_1416	PMA	LOOM
http://purl.obolibrary.org/obo/NCIT_C62078	BERO	LOOM
http://www.ifomis.org/acgt/1.0#Tamoxifen	ACGT-MO	LOOM
http://purl.jp/bio/4/id/200906003583642183	IOBC	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148024	INBANCIDO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148024	ODAE	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148024	CIDO	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003102	LOINC	LOOM
https://go.drugbank.com/drugs/DB00675	MDM	LOOM
rgo:24944	GAMUTS	LOOM
http://purl.obolibrary.org/obo/OMIT_0014488	OMIT	LOOM
http://www.projecthalo.com/aura#Tamoxifen	AURA	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148024	NDFRT	LOOM
http://www.semanticweb.org/cjf/ontologies/2022/8/NeuralReprogrammingOntology(NRO)#Tamoxifen	NRO	LOOM
http://www.co-ode.org/ontologies/galen#Tamoxifen	GALEN	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.389.150.700.900	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LP18484-3	LOINC	LOOM
http://purl.bioontology.org/ontology/RCD/he4..	RCD	LOOM
http://purl.bioontology.org/ontology/VANDF/4019939	VANDF	LOOM