Medical Action Ontology

Last uploaded: February 5, 2024
Preferred Name

actin filament

Synonyms

microfilament

Definitions

A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.

ID

http://purl.obolibrary.org/obo/GO_0005884

database_cross_reference

NIF_Subcellular:sao1588493326

Wikipedia:Actin

FMA:63850

definition

A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.

has_exact_synonym

microfilament

hasOBONamespace

cellular_component

id

GO:0005884

label

actin filament

notation

GO:0005884

part_of

http://purl.obolibrary.org/obo/GO_0015629

prefLabel

actin filament

treeView

http://purl.obolibrary.org/obo/GO_0015629

subClassOf

http://purl.obolibrary.org/obo/GO_0099513

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http://purl.obolibrary.org/obo/GO_0005884 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 XPO SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 FYPO SAME_URI
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http://purl.obolibrary.org/obo/GO_0005884 HOIP SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 UBERON SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 PATO SAME_URI
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http://purl.obolibrary.org/obo/GO_0005884 GO-EXT SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 FOVT SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 CCO SAME_URI
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http://purl.obolibrary.org/obo/GO_0005884 GEXO SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 PHAGE SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 CMPO SAME_URI
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http://purl.obolibrary.org/obo/GO_0005884 NIFDYS SAME_URI
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http://purl.obolibrary.org/obo/GO_0005884 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 KTAO SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 REGN_GO SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 RETO SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 AISM SAME_URI
http://purl.obolibrary.org/obo/GO_0005884 NMDCO SAME_URI
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http://purl.obolibrary.org/obo/GO_0005884 GO LOOM
http://purl.obolibrary.org/obo/GO_0005884 ZP LOOM
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http://purl.obolibrary.org/obo/GO_0005884 NIGO LOOM
http://purl.obolibrary.org/obo/GO_0005884 RBO LOOM
http://purl.obolibrary.org/obo/GO_0005884 GO-EXT LOOM
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http://purl.obolibrary.org/obo/GO_0005884 REXO LOOM
http://purl.obolibrary.org/obo/GO_0005884 GEXO LOOM
http://purl.obolibrary.org/obo/GO_0005884 PHAGE LOOM
http://purl.obolibrary.org/obo/GO_0005884 CMPO LOOM
http://purl.obolibrary.org/obo/GO_0005884 PCL LOOM
http://purl.obolibrary.org/obo/GO_0005884 NIFDYS LOOM
http://purl.obolibrary.org/obo/GO_0005884 BERO LOOM
http://purl.obolibrary.org/obo/GO_0005884 NBO LOOM
http://purl.obolibrary.org/obo/GO_0005884 HHEAR LOOM
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http://purl.obolibrary.org/obo/GO_0005884 NIFSTD LOOM
http://purl.obolibrary.org/obo/GO_0005884 KTAO LOOM
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http://purl.obolibrary.org/obo/GO_0005884 NMDCO LOOM
http://purl.org/obo/owl/GO#GO_0005884 BIOMODELS LOOM
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