loading...| Preferred Name |
Dandy-Walker malformation |
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| Synonyms |
Dandy-Walker cyst Dandy-walker anomaly |
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| Definitions |
A congenital brain malformation typically characterized by incomplete formation of the cerebellar vermis, dilation of the fourth ventricle, and enlargement of the posterior fossa. In layman's terms, Dandy Walker malformation is a cyst in the cerebellum (typically symmetrical) that is involved with the fourth ventricle. This may interfere with the ability to drain cerebrospinal fluid from the brain, resulting in hydrocephalus. Dandy Walker cysts are formed during early embryonic development, while the brain forms. The cyst in the cerebellum typically has several blood vessels running through it connecting to the brain, thereby prohibiting surgical removal. |
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| ID |
http://purl.obolibrary.org/obo/HP_0001305 |
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| database_cross_reference |
SNOMEDCT_US:14447001 MSH:D003616 UMLS:C0010964 |
|
| definition |
A congenital brain malformation typically characterized by incomplete formation of the cerebellar vermis, dilation of the fourth ventricle, and enlargement of the posterior fossa. In layman's terms, Dandy Walker malformation is a cyst in the cerebellum (typically symmetrical) that is involved with the fourth ventricle. This may interfere with the ability to drain cerebrospinal fluid from the brain, resulting in hydrocephalus. Dandy Walker cysts are formed during early embryonic development, while the brain forms. The cyst in the cerebellum typically has several blood vessels running through it connecting to the brain, thereby prohibiting surgical removal. |
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| has_alternative_id |
HP:0006809 HP:0001313 |
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| has_exact_synonym |
Dandy-Walker cyst Dandy-walker anomaly |
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| has_obo_namespace |
human_phenotype |
|
| id |
HP:0001305 |
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| label |
Dandy-Walker malformation |
|
| notation |
HP:0001305 |
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| prefLabel |
Dandy-Walker malformation |
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| treeView |
http://purl.obolibrary.org/obo/HP_0001320 http://purl.obolibrary.org/obo/HP_0005445 |
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| subClassOf |
http://purl.obolibrary.org/obo/HP_0001320 http://purl.obolibrary.org/obo/HP_0005445 |