Human Phenotype Ontology

Last uploaded: April 26, 2024
Preferred Name

Schwannoma

Synonyms

Schwannomas

Schwann cell tumour

Neurinoma

Schwann cell tumor

Neurolemmoma

Neurilemmoma

Definitions

A benign nerve sheath tumor composed of Schwann cells. Glial cells are cells that support nerve cells. Schwann cells wrap around the axon to form the myelin sheath. Schwann cells are involved in many important aspects of peripheral nerve biology; the conduction of nervous impulses along axons, nerve development and regeneration, trophic support for neurons, production of the nerve extracellular matrix and presentation of antigens to T-lymphocytes. Charcot-Marie-Tooth disease (CMT), Guillain-Barre syndrome (GBS), schwannomatosis and chronic inflammatory demyelinating polyneuropathy (CIDP) are all neuropathies involving Schwann cells.

ID

http://purl.obolibrary.org/obo/HP_0100008

comment

Glial cells are cells that support nerve cells. Schwann cells wrap around the axon to form the myelin sheath. Schwann cells are involved in many important aspects of peripheral nerve biology; the conduction of nervous impulses along axons, nerve development and regeneration, trophic support for neurons, production of the nerve extracellular matrix and presentation of antigens to T-lymphocytes. Charcot-Marie-Tooth disease (CMT), Guillain-Barre syndrome (GBS), schwannomatosis and chronic inflammatory demyelinating polyneuropathy (CIDP) are all neuropathies involving Schwann cells.

creation_date

2010-05-14T09:13:07Z

creator

https://orcid.org/0009-0006-4530-3154

database_cross_reference

UMLS:C0027809

MSH:D009442

SNOMEDCT_US:404022001

SNOMEDCT_US:985004

definition

A benign nerve sheath tumor composed of Schwann cells.

has_exact_synonym

Schwann cell tumour

Neurinoma

Schwann cell tumor

Neurolemmoma

Neurilemmoma

has_obo_namespace

human_phenotype

has_related_synonym

Schwannomas

id

HP:0100008

label

Schwannoma

notation

HP:0100008

prefLabel

Schwannoma

treeView

http://purl.obolibrary.org/obo/HP_0100007

subClassOf

http://purl.obolibrary.org/obo/HP_0100007

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