Preferred Name |
Insulin |
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Synonyms |
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Definitions |
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (glycogenolysis; gluconeogenesis) and indirectly by suppressing glucagon secretion and lipolysis. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (diabetes mellitus, type 1). |
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ID |
http://purl.obolibrary.org/obo/HIO_0000186 |
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description |
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (glycogenolysis; gluconeogenesis) and indirectly by suppressing glucagon secretion and lipolysis. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (diabetes mellitus, type 1). |
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created_by |
Jade Hotchkiss |
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creation_date |
2019-06-10T19:50:47.249828Z |
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database cross reference |
MESH:D007328 |
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definition source | ||
existence in other ontologies |
Sufficient |
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hasExactSynonym |
Sodium Insulin |
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label |
Insulin |
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prefixIRI |
HIO:0000186 |
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prefLabel |
Insulin |
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subClassOf |