loading...| Preferred Name |
Adaptive Immune System |
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| Synonyms |
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| Definitions |
Reviewed: Trowsdale, J, Bluestone, JA, Elliott, T, Esensten, J, Heemskerk, JW, 2011-05-28 Adaptive immunity refers to antigen-specific immune response efficiently involved in clearing the pathogens. The adaptive immune system is comprised of B and T lymphocytes that express receptors with remarkable diversity tailored to recognize aspects of particular pathogens or antigens. During infection, dendritic cells (DC) which act as sentinels in the peripheral tissues recognize and pick up the pathogen in the form of antigenic determinants and then process these antigens and present them to T cells. These T cells of appropriate specificity respond to the antigen, and either kill the pathogen directly or secrete cytokines that will stimulate B lymphocyte response. B cells provide humoral immunity by secreting antibodies specific for the pathogen or antigen. Authored: de Bono, B, Garapati, P V, Jupe, S, May, B, 2011-05-22 Edited: de Bono, B, Garapati, P V, Jupe, S, May, B, 2011-05-22 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0026239 |
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| comment |
Reviewed: Trowsdale, J, Bluestone, JA, Elliott, T, Esensten, J, Heemskerk, JW, 2011-05-28 Adaptive immunity refers to antigen-specific immune response efficiently involved in clearing the pathogens. The adaptive immune system is comprised of B and T lymphocytes that express receptors with remarkable diversity tailored to recognize aspects of particular pathogens or antigens. During infection, dendritic cells (DC) which act as sentinels in the peripheral tissues recognize and pick up the pathogen in the form of antigenic determinants and then process these antigens and present them to T cells. These T cells of appropriate specificity respond to the antigen, and either kill the pathogen directly or secrete cytokines that will stimulate B lymphocyte response. B cells provide humoral immunity by secreting antibodies specific for the pathogen or antigen. Authored: de Bono, B, Garapati, P V, Jupe, S, May, B, 2011-05-22 Edited: de Bono, B, Garapati, P V, Jupe, S, May, B, 2011-05-22 |
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| definition source |
Pubmed16551257 Reactome, http://www.reactome.org Pubmed11861602 Pubmed21682741 |
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| label |
Adaptive Immune System |
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| located_in | ||
| prefixIRI |
HINO:0026239 |
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| prefLabel |
Adaptive Immune System |
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| seeAlso |
ReactomeREACT_75774 Reactome Database ID Release 431280218 |
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| subClassOf | ||
| has_part |
http://purl.obolibrary.org/obo/HINO_0022374 http://purl.obolibrary.org/obo/HINO_0022379 http://purl.obolibrary.org/obo/HINO_0022392 http://purl.obolibrary.org/obo/HINO_0022397 http://purl.obolibrary.org/obo/HINO_0022399 |