Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)

Synonyms
Definitions

Reviewed: Chao, JA, 2010-05-30 Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs) bind specific sets of RNA and regulate their translation, stability, and subcellular localization. IGF2BP1, IGF2BP2, and IGF2BP3 bind about 8400 protein-coding transcripts. The target RNAs contain the sequence motif CAUH (where H is A, U, or, C) and binding of IGFBPs increases the stability of the target RNAs. Edited: May, B, 2009-07-04 Authored: May, B, 2009-07-04 Reviewed: Singer, RH, 2010-05-30

ID

http://purl.obolibrary.org/obo/HINO_0016043

comment

Reviewed: Chao, JA, 2010-05-30

Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs) bind specific sets of RNA and regulate their translation, stability, and subcellular localization. IGF2BP1, IGF2BP2, and IGF2BP3 bind about 8400 protein-coding transcripts. The target RNAs contain the sequence motif CAUH (where H is A, U, or, C) and binding of IGFBPs increases the stability of the target RNAs.

Edited: May, B, 2009-07-04

Authored: May, B, 2009-07-04

Reviewed: Singer, RH, 2010-05-30

definition source

Pubmed9891060

Pubmed17652133

Reactome, http://www.reactome.org

Pubmed15601260

Pubmed11713986

Pubmed20371350

Pubmed16541107

label

Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)

located_in

http://purl.obolibrary.org/obo/NCBITaxon_9606

prefixIRI

HINO:0016043

prefLabel

Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)

seeAlso

ReactomeREACT_22166

Reactome Database ID Release 43428359

subClassOf

http://purl.obolibrary.org/obo/INO_0000021

has_part

http://purl.obolibrary.org/obo/HINO_0008759

http://purl.obolibrary.org/obo/HINO_0008760

http://purl.obolibrary.org/obo/HINO_0008761

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http://scai.fraunhofer.de/PWDICT#ID2070 PTS LOOM