Preferred Name |
Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) |
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Synonyms |
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Definitions |
Reviewed: Chao, JA, 2010-05-30 Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs) bind specific sets of RNA and regulate their translation, stability, and subcellular localization. IGF2BP1, IGF2BP2, and IGF2BP3 bind about 8400 protein-coding transcripts. The target RNAs contain the sequence motif CAUH (where H is A, U, or, C) and binding of IGFBPs increases the stability of the target RNAs. Edited: May, B, 2009-07-04 Authored: May, B, 2009-07-04 Reviewed: Singer, RH, 2010-05-30 |
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ID |
http://purl.obolibrary.org/obo/HINO_0016043 |
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comment |
Reviewed: Chao, JA, 2010-05-30 Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs) bind specific sets of RNA and regulate their translation, stability, and subcellular localization. IGF2BP1, IGF2BP2, and IGF2BP3 bind about 8400 protein-coding transcripts. The target RNAs contain the sequence motif CAUH (where H is A, U, or, C) and binding of IGFBPs increases the stability of the target RNAs. Edited: May, B, 2009-07-04 Authored: May, B, 2009-07-04 Reviewed: Singer, RH, 2010-05-30 |
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definition source |
Pubmed9891060 Pubmed17652133 Reactome, http://www.reactome.org Pubmed15601260 Pubmed11713986 Pubmed20371350 Pubmed16541107 |
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label |
Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) |
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located_in | ||
prefixIRI |
HINO:0016043 |
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prefLabel |
Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) |
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seeAlso |
ReactomeREACT_22166 Reactome Database ID Release 43428359 |
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subClassOf | ||
has_part |
http://purl.obolibrary.org/obo/HINO_0008759 |