loading...| Preferred Name |
diethylstilbestrol |
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| Synonyms |
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| Definitions |
A synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_41922 |
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| ATC Code |
L02AA01 |
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| ChEBI ID | ||
| definition |
A synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. |
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| has database cross reference | ||
| is referenced by | ||
| label |
diethylstilbestrol |
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| Library of Congress Subject Headings | ||
| MeSH Descriptor ID | ||
| name |
DES |
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| NCI Thesaurus ID | ||
| prefixIRI |
CHEBI:41922 |
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| prefLabel |
diethylstilbestrol |
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| short name |
DES |
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| SNOMED CT Identifier | ||
| subClassOf |