loading...| Preferred Name |
diphtheria |
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| Synonyms |
corynebacterium infection Corynebacterium infection diphtheria |
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| Definitions |
A primary bacterial infectious disease that is characterized by sore throat, low fever, and an adherent membrane (a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. A milder form of diphtheria can be restricted to the skin. It is caused by Corynebacterium diphtheriae, an aerobic Gram-positive bacterium. Diphtheria toxin spreads through the bloodstream and can lead to potentially life-threatening complications that affect other organs of the body, such as the heart and kidneys. A Gram-positive bacterial infection caused by Corynebacterium diphtheriae. It usually involves the oral cavity, pharynx, and nasal cavity. Patients develop pseudomembranes in the affected areas and manifest signs and symptoms of an upper respiratory infection. The diphtheria toxin may cause myocarditis, polyneuritis, and other systemic effects. |
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| ID |
http://www.ebi.ac.uk/efo/EFO_0005549 |
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| closeMatch | ||
| database_cross_reference |
MedDRA:10013025 MedDRA:10013023 NCIt:C34541 SNOMEDCT:397428000 MeSH:D004165 ICD9:032 ICD10CM:A36 UMLS:C0012546 GARD:1875 ICD10CM:A36.3 MESH:D004165 SCTID:397428000 ICD9:032.9 MONDO:0005504 NCIT:C34541 DOID:11405 Orphanet:1679 |
|
| definition |
A primary bacterial infectious disease that is characterized by sore throat, low fever, and an adherent membrane (a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. A milder form of diphtheria can be restricted to the skin. It is caused by Corynebacterium diphtheriae, an aerobic Gram-positive bacterium. Diphtheria toxin spreads through the bloodstream and can lead to potentially life-threatening complications that affect other organs of the body, such as the heart and kidneys. A Gram-positive bacterial infection caused by Corynebacterium diphtheriae. It usually involves the oral cavity, pharynx, and nasal cavity. Patients develop pseudomembranes in the affected areas and manifest signs and symptoms of an upper respiratory infection. The diphtheria toxin may cause myocarditis, polyneuritis, and other systemic effects. |
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| exactMatch |
http://identifiers.org/snomedct/397428000 http://identifiers.org/mesh/D004165 http://purl.obolibrary.org/obo/DOID_11405 http://purl.obolibrary.org/obo/Orphanet_1679 http://purl.obolibrary.org/obo/NCIT_C34541 |
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| gwas_trait |
true |
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| has_exact_synonym |
corynebacterium infection Corynebacterium infection diphtheria |
|
| id |
EFO:0005549 |
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| in_subset |
http://purl.obolibrary.org/obo/mondo#ordo_disease http://purl.obolibrary.org/obo/mondo#rare http://purl.obolibrary.org/obo/mondo#nord_rare |
|
| label |
diphtheria |
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| notation |
EFO:0005549 |
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| prefLabel |
diphtheria |
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| see also | ||
| subClassOf | ||
| has_participant |