loading...| Preferred Name |
STK11 gene |
|
| Synonyms |
|
|
| Definitions |
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
|
| ID |
http://www.drugtargetontology.org/dto/DTO_03200496 |
|
| definition |
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
|
| entrez_xref |
6794 |
|
| geneSymbol |
STK11 |
|
| geneSynonym |
LKB1 PJS |
|
| label |
STK11 gene |
|
| prefixIRI |
dto:DTO_03200496 |
|
| prefLabel |
STK11 gene |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18253 | NCIT | LOOM | |
| http://purl.obolibrary.org/obo/NCIT_C18253 | BERO | LOOM | |
| http://www.semanticweb.org/ADMO#STK11_gene | ADMO | LOOM | |
| http://purl.bioontology.org/ontology/LNC/LP71163-7 | LOINC | LOOM |
This ontology integrates with OntoloBridge, allowing community users to suggest additions to the public ontology. Complete the template below to submit a term request directly to the ontology maintainer.
Term Label (required)
Suggested term name. If a term can be described with multiple synonyms, only list the preferred name here.
Term description (required)
A brief definition, description, or usage of your suggested term. Additional term synonyms may be listed in this section.
Superclass (required)
The parent term of the suggested term. The parent term should be an existing entry of the current ontology. The superclass can be selected directly from Bioportal's Classes tree viewer.
References (optional)
Provide evidence for the existence of the requested term such as Pubmed IDs of papers or links to other resources that describe the term.
Justification (optional)
Provide any additional information about the requested term here.