loading...| Preferred Name |
prion disease |
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| Synonyms |
prion disease pathway spongiform encephalopathy prion protein disease prion induced disorder |
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| Definitions |
Editor note: check relationship to spongiform encephalopathy NCIT:C27585 A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal. |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0005429 |
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| comment |
Editor note: check relationship to spongiform encephalopathy NCIT:C27585 |
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| has_exact_synonym |
prion disease pathway spongiform encephalopathy prion protein disease prion induced disorder |
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| label |
prion disease |
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| prefixIRI |
MONDO:0005429 |
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| prefLabel |
prion disease |
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| textual definition |
A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal. |
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| subClassOf |