The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

deferasirox
Synonyms

C21H15N3O4

4-[bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid
ID

http://purl.obolibrary.org/obo/dinto_DB01609
ATCCode

V03AC03
CASRN

201530-41-8
chelates

http://purl.obolibrary.org/obo/dinto_3067
DBBrand

exjade
DBSynonym

deferasiroxum [inn-latin]

icl 670
Definition

Deferasirox is an oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. It is the first oral medication approved in the USA for this purpose.
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0001365

http://purl.obolibrary.org/obo/OAE_0000476

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0001296

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000455

http://purl.obolibrary.org/obo/OAE_0001024

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0001126

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000789

http://purl.obolibrary.org/obo/OAE_0000968

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000344

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0001403

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000336

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000565

http://purl.obolibrary.org/obo/OAE_0000296

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0001364

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target

http://purl.obolibrary.org/obo/dinto_3067
InChI

InChI=1S/C21H15N3O4/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28/h1-12,25-26H,(H,27,28)
InChIKey

InChIKey=BOFQWVMAQOTZIW-UHFFFAOYSA-N
induces

http://purl.obolibrary.org/obo/dinto_0901
label

deferasirox
may interact with

http://purl.obolibrary.org/obo/dinto_DB01370

http://purl.obolibrary.org/obo/CHEBI_59173
prefixIRI

obo2:dinto_DB01609
prefLabel

deferasirox
SMILES

OC(=O)C1=CC=C(C=C1)N1N=C(N=C1C1=CC=CC=C1O)C1=CC=CC=C1O
Synonym

C21H15N3O4

4-[bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid
xref

Drugs Product Database (DPD):1926756

National Drug Code Directory:0078-0468-15

PharmGKB:PA164760843

PubChem Substance:46506791

Drugs.com:http://www.drugs.com/cdi/deferasirox.html

PubChem Compound:5493381

ChemSpider:4591431

Wikipedia:http://en.wikipedia.org/wiki/Deferasirox

RxList:http://www.rxlist.com/cgi/generic/exjade.htm
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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