The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	nifedipine
Synonyms	Adapine Nifedipine C17H18N2O6 Procardia Nifedipres 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate nifedipinum Adalat Nifecor 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate nifedipino nifedipine Coracten Nifecard
ID	http://purl.obolibrary.org/obo/CHEBI_7565
AHFScode	24:28.08
ATCCode	C08CA05
binds	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2962 http://purl.obolibrary.org/obo/dinto_2965 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0753 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_2260 http://purl.obolibrary.org/obo/dinto_2849 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_2979 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_3508 http://purl.obolibrary.org/obo/dinto_1027 http://purl.obolibrary.org/obo/dinto_0588 http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_0465 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1956
CASRN	21829-25-4
DBBrand	nifidine nifedipres aprical calcigard nicardia adalat gits 30 sepamit nifangin adalat oros anpine adalat gits cardionorm ecodipi procardia nifedine tibricol chronadalate dignokonstant adalat 5 nifedirex lp nifdemin adalat 10 nifedepat alpha-nifedipine retard fedcor calcibloc nifelat q adalat la adalat crono adalate coral adalat 20 adalat lp alonix zenusin depin fenihidin hexadilat nifecor alat calcilat coracten pidilat cordafen cordalat oxcord nifelate nifedin nifedicor kordafen fenihidine cordilan adalat nedipin duranifin anifed adalat cc dipinkor orix alonix s chronadalate lp adalat ft niphedipine cardilat angipec bonacid cordicant introcar corotrend fenamon fenamon sr myogard nifensar xl nifelan nificard alfadal cordaflex apo-nifed adapress n1fedilat cordipin citilat nifedipine retard adalat cr adapine nifipen adalat pa procardia xl nifelat nifar ecodipin e corynphar hadipin fedcor retard corinfar nifecard ecodipin camont aldipin macorel glopir dilafed cardifen nifebene adalat retard megalat
DBname	nifedipine
Definition	A dihydropyridine that has formula C17H18N2O6.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0001373 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000303 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000617 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0001369 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000412 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000935 http://purl.obolibrary.org/obo/OAE_0001339 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000050 http://purl.obolibrary.org/obo/OAE_0000207 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000690 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000517 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0001200 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000405 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0001356 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000358 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0000766 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000811 http://purl.obolibrary.org/obo/OAE_0000350 http://purl.obolibrary.org/obo/OAE_0000304
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2962 http://purl.obolibrary.org/obo/dinto_2965 http://purl.obolibrary.org/obo/dinto_2979 http://purl.obolibrary.org/obo/dinto_3508 http://purl.obolibrary.org/obo/dinto_1027
has role	http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_66993 http://purl.obolibrary.org/obo/CHEBI_38215
InChI	InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
InChIKey	InChIKey=HYIMSNHJOBLJNT-UHFFFAOYSA-N
induces	http://purl.obolibrary.org/obo/dinto_0588 http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_0465
inhibits	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2962 http://purl.obolibrary.org/obo/dinto_2965 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0753 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_2260 http://purl.obolibrary.org/obo/dinto_2849 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_2979 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_3508 http://purl.obolibrary.org/obo/dinto_1027
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1956
is substrate of	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2496 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1440
is transported by	http://purl.obolibrary.org/obo/dinto_1440
label	nifedipine
may interact with	http://purl.obolibrary.org/obo/CHEBI_102524 http://purl.obolibrary.org/obo/dinto_DB00794 http://purl.obolibrary.org/obo/CHEBI_102166 http://purl.obolibrary.org/obo/dinto_DB00306 http://purl.obolibrary.org/obo/dinto_DB01355 http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/CHEBI_102216 http://purl.obolibrary.org/obo/CHEBI_8069 http://purl.obolibrary.org/obo/dinto_DB00312 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/dinto_DB01354 http://purl.obolibrary.org/obo/dinto_DB01323 http://purl.obolibrary.org/obo/CHEBI_16796 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB00237 http://purl.obolibrary.org/obo/dinto_DB01352 http://purl.obolibrary.org/obo/CHEBI_6758 http://purl.obolibrary.org/obo/CHEBI_3720 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/CHEBI_63629 http://purl.obolibrary.org/obo/CHEBI_63628 http://purl.obolibrary.org/obo/dinto_DB01351 http://purl.obolibrary.org/obo/dinto_DB00382 http://purl.obolibrary.org/obo/dinto_DB01404 http://purl.obolibrary.org/obo/CHEBI_28593 http://purl.obolibrary.org/obo/dinto_DB01369 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/dinto_DB01346 http://purl.obolibrary.org/obo/dinto_DB01353 http://purl.obolibrary.org/obo/dinto_DB01341 http://purl.obolibrary.org/obo/CHEBI_9073 http://purl.obolibrary.org/obo/dinto_DB00976 http://purl.obolibrary.org/obo/CHEBI_45783
prefixIRI	obo2:CHEBI_7565
prefLabel	nifedipine
SMILES	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC
Synonym	Adapine Nifedipine C17H18N2O6 Procardia Nifedipres 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate nifedipinum Adalat Nifecor 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate nifedipino nifedipine Coracten Nifecard
xref	RxList:http://www.rxlist.com/cgi/generic2/nifedip.htm PubChem Compound:4485 Wikipedia:http://en.wikipedia.org/wiki/Nifedipine PubChem Substance:46505103 KEGG COMPOUND:C07266 DrugBank:DB01115 Beilstein:497773 BindingDB:50000778 Drugs.com:http://www.drugs.com/nifedipine.html IUPHAR:2514 Wikipedia:Nifedipine Guide To Pharmacology:2514 CASRN:21829-25-4 PharmGKB:PA450631 ChEMBL:519596 ChEBI:7565 National Drug Code Directory:0378-3475-01 Drugs Product Database (DPD):2235898 ChemSpider:4330 NIST Chemistry WebBook:21829-25-4 KEGG DRUG:D00437
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_7565	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	BAO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	DIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7565	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	CHEBI	LOOM
http://purl.obolibrary.org/obo/XCO_0000611	XCO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009543	RH-MESH	LOOM
https://go.drugbank.com/drugs/DB01115	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.725.203.540	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LP17866-2	LOINC	LOOM
http://purl.bioontology.org/ontology/SNMI/C-80430	SNMI	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028066	OCHV	LOOM
http://www.co-ode.org/ontologies/galen#Nifedipine	GALEN	LOOM
http://bmi.utah.edu/ontologies/hfontology/C0028066	HFO	LOOM
http://purl.jp/bio/4/id/200906048665783463	IOBC	LOOM
http://purl.bioontology.org/ontology/VANDF/4018390	VANDF	LOOM
http://purl.bioontology.org/ontology/RCD/bl8..	RCD	LOOM
http://purl.bioontology.org/ontology/CSP/2509-8393	CRISP	LOOM
http://purl.obolibrary.org/obo/MESH_D009543	BERO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8713	OCHV	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	BAO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_7565	DIDEO	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146717	NDFRT	LOOM
http://www.drugbank.ca/drugs/DB01115	FTC	LOOM
http://purl.bioontology.org/ontology/NDDF/000710	NDDF	LOOM
http://stirdf.jst.go.jp/id/200907064581242156	IOBC	LOOM
http://purl.obolibrary.org/obo/OMIT_0010566	OMIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C29290	BERO	LOOM
http://mimi.case.edu/ontologies/2009/9/DrugOntology#nifedipine	SDO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018328	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387490003	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU062929	LOINC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29290	NCIT	LOOM
http://purl.bioontology.org/ontology/MESH/D009543	MESH	LOOM
http://purl.bioontology.org/ontology/RXNORM/7417	RXNORM	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146717	OCVDAE	LOOM
http://purl.bioontology.org/ontology/ATC/C08CA05	ATC	LOOM