loading...| Preferred Name |
triamcinolone acetonide |
|
| Synonyms |
9alpha-fluoro-16alpha-hydroxyprednisolone 16alpha,17alpha-acetonide 9alpha-fluoro-11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione 9alpha-fluoro-11beta,21-dihydroxy-16alpha,17-isopropylidenedioxy-1,4-pregnadiene,3,20-dione (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one C21H27FO6 9-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide C24H31FO6 (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one 9alpha-fluoro-16alpha-17alpha-isopropylidenedioxy-Delta-1-hydrocortisone 9alpha-fluoro-16alpha-17alpha-isopropyledenedioxyprednisolone Triamcinolone 16,17-acetonide |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_71418 |
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| activates | ||
| AHFScode |
84:06.00 52:08.08 68:04.00 |
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| altId |
CHEBI:9668 |
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| ATCCode |
R03BA06 R01AD11 D07XB02 S01BA05 C05AA12 H02AB08 A01AC01 D07AB09 |
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| binds | ||
| CASRN |
124-94-7 |
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| DBBrand |
trymex kenalog-h triamcinlon nasacort hfa tristoject triderm triamcinolon trilone oralone kenalog-10 nasacort triatex cinolone aristocort a aristocort tablets volon orion adcortyl celeste omcilon sk-triamcinolone omicilon triacet tricortale triacort rodinolone azmacort triamcet kenalog-40 delphicort cinolone-t tri-nasal kenalog triam-tablinen flutex aristogel kenalog in orabase aristocort volon a fougera oracort kenacort-ag nasacort aq kenacort aristospan ledercort |
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| DBname |
triamcinolone |
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| DBSynonym |
triamcinolone diacetate fluoxyprednisolone triamcinolona [inn-spanish] fluoxiprednisolone tiamcinolonum [inn-latin] triamcinolonum [inn] triamcinalone triamcinolone acetonide triamcinolone hexacetonide |
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| Definition |
A synthetic glucocorticoid that is the 16,17-acetonide of triamcinolone. Used to treat various skin infections. |
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| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1 InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1 |
|
| InChIKey |
InChIKey=YNDXUCZADRHECN-JNQJZLCISA-N InChIKey=GFNANZIMVAIWHM-OBYCQNJPSA-N |
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| induces | ||
| inhibits | ||
| is metabolised by | ||
| label |
triamcinolone acetonide |
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| prefixIRI |
obo2:CHEBI_71418 |
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| prefLabel |
triamcinolone acetonide |
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| SMILES |
[H][C@@]12C[C@@H](O)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C [H][C@@]12C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |
|
| Synonym |
9alpha-fluoro-16alpha-hydroxyprednisolone 16alpha,17alpha-acetonide 9alpha-fluoro-11beta,21-dihydroxy-16alpha,17alpha-isopropylidenedioxypregna-1,4-diene-3,20-dione 9alpha-fluoro-11beta,21-dihydroxy-16alpha,17-isopropylidenedioxy-1,4-pregnadiene,3,20-dione (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one C21H27FO6 9-fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione-16,17-acetonide C24H31FO6 (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one 9alpha-fluoro-16alpha-17alpha-isopropylidenedioxy-Delta-1-hydrocortisone 9alpha-fluoro-16alpha-17alpha-isopropyledenedioxyprednisolone Triamcinolone 16,17-acetonide |
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| xref |
Drugs Product Database (DPD):2229540 Guide To Pharmacology:2870 ChemSpider:29046 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/azm1044.shtml ChEMBL:519622 Wikipedia:Triamcinolone_acetonide Drugs.com:http://www.drugs.com/cdi/triamcinolone-spray.html KEGG COMPOUND:C08183 PubChem Substance:46507950 DrugBank:DB00620 RxList:http://www.rxlist.com/cgi/generic/triamaer.htm Reaxys:60069 National Drug Code Directory:0781-3243-75 Patent:US2008118586 KEGG DRUG:D00983 PubChem Compound:31307 Patent:US2008139545 Wikipedia:http://en.wikipedia.org/wiki/Triamcinolone PharmGKB:PA451749 CASRN:76-25-5 IUPHAR:2870 |
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| subClassOf |