The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	oxaliplatin
Synonyms	oxaliplatin oxaliplatine oxaliplatinum (3aR,7aR)-octahydro-2',5'-dioxaspiro[cyclohexa[d]1,3-diaza-2-platinacyclopentane-2,1'-cyclopentane]-3',4'-dione oxaliplatino oxalato(1,2-diaminocyclohexane)platinum(II) C8H12N2O4Pt (SP-4-2)[(1R,2R)-cyclohexane-1,2-diamine-kappa(2)N,N'][ethanedioato(2-)-kappa(2)O(1),O(2)]platinum (SP-4-2-(1R-trans))-(1,2-cyclohexanediamine-N,N')(ethanedioato(2-)-O,O')platinum Oxaliplatin C6H14N2.C2O4.Pt C8H14N2O4Pt Eloxatin
ID	http://purl.obolibrary.org/obo/CHEBI_31941
AHFScode	10:00
ATCCode	L01XA03
CASRN	61825-94-3
DBBrand	eloxatin
DBname	oxaliplatin
DBSynonym	diaminocyclohexane oxalatoplatinum l-ohp oxalatoplatin oxalatoplatinum
Definition	A platinum coordination entity that has formula C6H14N2.C2O4.Pt.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0001154 http://purl.obolibrary.org/obo/OAE_0001098 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001510 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000839 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000617 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000900 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001360 http://purl.obolibrary.org/obo/OAE_0000801 http://purl.obolibrary.org/obo/OAE_0001369 http://purl.obolibrary.org/obo/OAE_0000549 http://purl.obolibrary.org/obo/OAE_0001707 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0001013 http://purl.obolibrary.org/obo/OAE_0001012 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0001095 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0001370 http://purl.obolibrary.org/obo/OAE_0000333 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0001025 http://purl.obolibrary.org/obo/OAE_0000677 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000050 http://purl.obolibrary.org/obo/OAE_0001288 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000476 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0001055 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000690 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0000943 http://purl.obolibrary.org/obo/OAE_0001322 http://purl.obolibrary.org/obo/OAE_0000434 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0001341 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001135 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000533 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000898 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000302 http://purl.obolibrary.org/obo/OAE_0001356 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000185 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000347 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0000669 http://purl.obolibrary.org/obo/OAE_0000514 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0000358 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0000456 http://purl.obolibrary.org/obo/OAE_0001044 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0001054 http://purl.obolibrary.org/obo/OAE_0000506 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2873
has role	http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_25435
InChI	InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2/t5-,6-;;/m1../s1 InChI=1S/C6H12N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-8H,1-4H2;(H,3,4)(H,5,6);/q-2;;+4/p-2/t5-,6-;;/m1../s1
InChIKey	InChIKey=ZROHGHOFXNOHSO-BNTLRKBRSA-L InChIKey=DWAFYCQODLXJNR-BNTLRKBRSA-L
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2243 http://purl.obolibrary.org/obo/dinto_3307 http://purl.obolibrary.org/obo/dinto_3089 http://purl.obolibrary.org/obo/dinto_1151 http://purl.obolibrary.org/obo/dinto_1150 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0269 http://purl.obolibrary.org/obo/dinto_0285 http://purl.obolibrary.org/obo/dinto_0282 http://purl.obolibrary.org/obo/dinto_2897 http://purl.obolibrary.org/obo/dinto_0859
is transported by	http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1972 http://purl.obolibrary.org/obo/dinto_1970 http://purl.obolibrary.org/obo/dinto_1971 http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1776 http://purl.obolibrary.org/obo/dinto_1771
label	oxaliplatin
may interact with	http://purl.obolibrary.org/obo/CHEBI_63632 http://purl.obolibrary.org/obo/dinto_DB00072
prefixIRI	obo2:CHEBI_31941
prefLabel	oxaliplatin
related with	http://purl.obolibrary.org/obo/dinto_2873
SMILES	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O [H][N]1([H])[C@@H]2CCCC[C@H]2[N]([H])([H])[Pt]11OC(=O)C(=O)O1
Synonym	oxaliplatin oxaliplatine oxaliplatinum (3aR,7aR)-octahydro-2',5'-dioxaspiro[cyclohexa[d]1,3-diaza-2-platinacyclopentane-2,1'-cyclopentane]-3',4'-dione oxaliplatino oxalato(1,2-diaminocyclohexane)platinum(II) C8H12N2O4Pt (SP-4-2)[(1R,2R)-cyclohexane-1,2-diamine-kappa(2)N,N'][ethanedioato(2-)-kappa(2)O(1),O(2)]platinum (SP-4-2-(1R-trans))-(1,2-cyclohexanediamine-N,N')(ethanedioato(2-)-O,O')platinum Oxaliplatin C6H14N2.C2O4.Pt C8H14N2O4Pt Eloxatin
xref	KEGG COMPOUND:C13258 Gmelin:1046012 PharmGKB:PA131285527 PubChem Substance:46509083 National Drug Code Directory:0703-3985-01 PubChem Compound:6857599 RxList:http://www.rxlist.com/cgi/generic/eloxatin.htm Gmelin:28892 KEGG DRUG:D01790 Drugs.com:http://www.drugs.com/cdi/oxaliplatin.html Wikipedia:http://en.wikipedia.org/wiki/Oxaliplatin CASRN:63121-00-6 ChemSpider:8062727 ChEBI:31941 CASRN:61825-94-3 DrugBank:DB00526
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_31941	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	FYPO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	OBA	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	HOIP	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	TXPO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	HINO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_31941	ODNAE	SAME_URI
http://purl.obolibrary.org/obo/XCO_0001285	XCO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	FYPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	HOIP	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	OBA	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/395814003	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148774	NDFRT	LOOM
http://purl.bioontology.org/ontology/RXNORM/32592	NLMVS	LOOM
http://purl.bioontology.org/ontology/RXNORM/32592	RXNORM	LOOM
http://purl.bioontology.org/ontology/MESH/D000077150	MESH	LOOM
http://www.co-ode.org/ontologies/galen#Oxaliplatin	GALEN	LOOM
http://ontology.lst.tfo.upm.es/SPT/chemo#Cancer_Therapy_Agent_Name@@11	HENEGEO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1181	NCIT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1181	ROO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0069717	OCHV	LOOM
http://purl.obolibrary.org/obo/NCIT_C1181	BERO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026261	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	TXPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	HINO	LOOM
http://purl.obolibrary.org/obo/CHEBI_31941	ODNAE	LOOM
http://purl.jp/bio/4/id/200906026539489483	IOBC	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148774	ODAE	LOOM
http://purl.bioontology.org/ontology/LNC/LP171626-7	LOINC	LOOM
http://purl.bioontology.org/ontology/NDDF/007166	NDDF	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042374	PDQ	LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_31941	NPO	LOOM
https://go.drugbank.com/drugs/DB00526	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C030110	RH-MESH	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14555	OCHV	LOOM
http://purl.bioontology.org/ontology/ATC/L01XA03	ATC	LOOM
http://purl.bioontology.org/ontology/VANDF/4021355	VANDF	LOOM