loading...| Preferred Name |
ceftriaxone |
|
| Synonyms |
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ceftriaxonum ceftriaxona ceftriaxone (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid C18H18N8O7S3 |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_29007 |
|
| AHFScode |
08:12.06.12 |
|
| altId |
CHEBI:23059 CHEBI:446214 CHEBI:3513 |
|
| ATCCode |
J01DD04 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_1920 http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_2004 http://purl.obolibrary.org/obo/dinto_4301 http://purl.obolibrary.org/obo/dinto_0520 |
|
| CASRN |
73384-59-5 |
|
| DBBrand |
rocephine biotrakson |
|
| DBname |
ceftriaxone |
|
| DBSynonym |
ceftriaxonum [inn-latin] ceftriazone ceftriaxona [inn-spanish] cefatriaxone |
|
| Definition |
A cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side groups. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0001154 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0001333 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0001425 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0001434 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0001152 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0001366 |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1 |
|
| InChIKey |
InChIKey=VAAUVRVFOQPIGI-SPQHTLEESA-N |
|
| induces | ||
| inhibits |
http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_1920 http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_2004 |
|
| label |
ceftriaxone |
|
| may interact with |
http://purl.obolibrary.org/obo/dinto_DB00994 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/dinto_DB01172 http://purl.obolibrary.org/obo/dinto_DB00258 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/dinto_DB00798 http://purl.obolibrary.org/obo/CHEBI_17076 http://purl.obolibrary.org/obo/dinto_DB00955 http://purl.obolibrary.org/obo/dinto_DB00684 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/dinto_DB01164 |
|
| prefixIRI |
obo2:CHEBI_29007 |
|
| prefLabel |
ceftriaxone |
|
| related with | ||
| SMILES |
[H][C@]12SCC(CSC3=NC(=O)C(=O)NN3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C1=CSC(N)=N1)C(O)=O [H][C@]12SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1csc(N)n1)C(O)=O |
|
| Synonym |
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ceftriaxonum ceftriaxona ceftriaxone (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid C18H18N8O7S3 |
|
| xref |
CASRN:73384-59-5 ChEMBL:183724 Drugs Product Database (DPD):657409 CiteXplore:11985490 CiteXplore:17129840 CiteXplore:18773080 CiteXplore:12830336 CiteXplore:16734965 MetaCyc:CPD-12294 CiteXplore:21425867 Drugs.com:http://www.drugs.com/cdi/ceftriaxone.html CiteXplore:15828439 CiteXplore:16082406 CiteXplore:12833570 CiteXplore:11067716 CiteXplore:11605716 CiteXplore:11432680 CiteXplore:17216959 CiteXplore:16185184 CiteXplore:17592517 CiteXplore:11875753 CiteXplore:18473104 CiteXplore:11642230 CiteXplore:19496200 CiteXplore:12426628 CiteXplore:15225244 RxList:http://www.rxlist.com/cgi/generic3/ceftriax.htm CiteXplore:19367098 CiteXplore:12868545 CiteXplore:17367972 Beilstein:6495519 CiteXplore:16161754 CiteXplore:12146884 PubChem Compound:5479530 CiteXplore:17347554 CiteXplore:15880392 CiteXplore:11856984 ChEBI:29007 CiteXplore:15886468 CiteXplore:12711894 CiteXplore:15106316 CiteXplore:15091234 CiteXplore:18246742 ChemSpider:4514885 PubChem Substance:46506458 DrugBank:DB01212 Patent:US4327210 CiteXplore:11760218 CiteXplore:12797390 CiteXplore:11529382 CiteXplore:17173674 CiteXplore:19008722 ChEMBL:16640341 Patent:GB2022090 CiteXplore:1384868 CiteXplore:15499067 CiteXplore:12569987 KEGG COMPOUND:C06683 CiteXplore:17226043 CiteXplore:19423473 KEGG DRUG:D07659 CiteXplore:18484523 PharmGKB:PA448866 CiteXplore:19649758 CiteXplore:11815759 CiteXplore:11285492 Wikipedia:Ceftriaxone CiteXplore:18611641 CiteXplore:15846537 CiteXplore:16602117 Wikipedia:http://en.wikipedia.org/wiki/Ceftriaxone CiteXplore:18676229 CiteXplore:18977704 CiteXplore:16118675 CiteXplore:11431418 National Drug Code Directory:0703-0315-03 Reaxys:6495519 CiteXplore:19625514 |
|
| subClassOf |