The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

ceftriaxone

Synonyms

(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

ceftriaxona

(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid

C18H18N8O7S3

ceftriaxonum

ceftriaxone

ID

http://purl.obolibrary.org/obo/CHEBI_29007

AHFScode

08:12.06.12

altId

CHEBI:3513

CHEBI:23059

CHEBI:446214

ATCCode

J01DD04

CASRN

73384-59-5

DBBrand

rocephine

biotrakson

DBname

ceftriaxone

DBSynonym

ceftriazone

cefatriaxone

ceftriaxona [inn-spanish]

ceftriaxonum [inn-latin]

Definition

A cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side groups.

has effect

http://purl.obolibrary.org/obo/OAE_0001425

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0001333

http://purl.obolibrary.org/obo/OAE_0000608

http://purl.obolibrary.org/obo/OAE_0001152

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000611

http://purl.obolibrary.org/obo/OAE_0000811

http://purl.obolibrary.org/obo/OAE_0000287

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0001434

http://purl.obolibrary.org/obo/OAE_0000308

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000194

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0001154

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000825

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000373

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1920

has role

http://purl.obolibrary.org/obo/CHEBI_36047

http://purl.obolibrary.org/obo/CHEBI_35625

InChI

InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1

InChIKey

InChIKey=VAAUVRVFOQPIGI-SPQHTLEESA-N

induces

http://purl.obolibrary.org/obo/dinto_3682

inhibits

http://purl.obolibrary.org/obo/dinto_1920

http://purl.obolibrary.org/obo/dinto_2004

http://purl.obolibrary.org/obo/dinto_4065

http://purl.obolibrary.org/obo/dinto_4301

http://purl.obolibrary.org/obo/dinto_0520

http://purl.obolibrary.org/obo/dinto_1975

label

ceftriaxone

may interact with

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/dinto_DB01164

http://purl.obolibrary.org/obo/CHEBI_17076

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/dinto_DB00798

http://purl.obolibrary.org/obo/dinto_DB01172

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/dinto_DB00258

http://purl.obolibrary.org/obo/CHEBI_2637

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/dinto_DB00955

http://purl.obolibrary.org/obo/dinto_DB00684

http://purl.obolibrary.org/obo/dinto_DB00994

prefixIRI

obo2:CHEBI_29007

prefLabel

ceftriaxone

related with

http://purl.obolibrary.org/obo/dinto_0217

SMILES

[H][C@]12SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O

[H][C@]12SCC(CSC3=NC(=O)C(=O)NN3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)C1=CSC(N)=N1)C(O)=O

Synonym

(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

ceftriaxona

(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid

C18H18N8O7S3

ceftriaxonum

ceftriaxone

xref

CiteXplore:16734965

CiteXplore:18977704

CiteXplore:15106316

CiteXplore:1384868

CiteXplore:17216959

Wikipedia:http://en.wikipedia.org/wiki/Ceftriaxone

CiteXplore:18484523

Drugs Product Database (DPD):657409

CiteXplore:12146884

CASRN:73384-59-5

CiteXplore:11642230

CiteXplore:18611641

CiteXplore:11985490

CiteXplore:11875753

Drugs.com:http://www.drugs.com/cdi/ceftriaxone.html

CiteXplore:16082406

CiteXplore:17592517

CiteXplore:11431418

CiteXplore:11815759

CiteXplore:11529382

CiteXplore:12797390

CiteXplore:17173674

CiteXplore:18246742

CiteXplore:15846537

CiteXplore:12711894

CiteXplore:15828439

CiteXplore:18676229

CiteXplore:15091234

CiteXplore:18773080

RxList:http://www.rxlist.com/cgi/generic3/ceftriax.htm

Reaxys:6495519

Patent:GB2022090

ChEBI:29007

CiteXplore:11760218

CiteXplore:21425867

MetaCyc:CPD-12294

CiteXplore:17129840

CiteXplore:16118675

CiteXplore:19423473

CiteXplore:19496200

CiteXplore:12426628

PharmGKB:PA448866

KEGG DRUG:D07659

CiteXplore:16161754

CiteXplore:12569987

CiteXplore:19649758

CiteXplore:11432680

CiteXplore:19625514

Patent:US4327210

CiteXplore:11067716

National Drug Code Directory:0703-0315-03

ChEMBL:16640341

CiteXplore:19008722

Wikipedia:Ceftriaxone

ChemSpider:4514885

CiteXplore:11285492

CiteXplore:17347554

ChEMBL:183724

Beilstein:6495519

CiteXplore:11856984

CiteXplore:19367098

CiteXplore:17367972

CiteXplore:15225244

DrugBank:DB01212

CiteXplore:18473104

KEGG COMPOUND:C06683

CiteXplore:12830336

CiteXplore:15880392

CiteXplore:15886468

PubChem Compound:5479530

CiteXplore:15499067

CiteXplore:16602117

CiteXplore:11605716

CiteXplore:17226043

CiteXplore:12833570

CiteXplore:16185184

PubChem Substance:46506458

CiteXplore:12868545

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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