loading...| Preferred Name |
nitroglycerin |
|
| Synonyms |
nitroglycerine trinitroglycerin Nitrostat Nitrolingual 1,2,3-propanetriyl nitrate Nitroglycerin 1,2,3-propanetrioltrinitrate NG glycerol trinitrate propane-1,2,3-triyl trinitrate nitroglycerol Natispray glycerin trinitrate trinitroglycerol glycerol, nitric acid triester 1,2,3-trinitrooxypropane Glyceryl trinitrate C3H5N3O9 Nitromist Transderm Nitro Rectogesic 2,3-bis(nitrooxy)propyl nitrate Nitro-Dur Minitran |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_28787 |
|
| activates | ||
| AHFScode |
92:02.00* 24:12.08 |
|
| altId |
CHEBI:25559 CHEBI:7595 |
|
| ATCCode |
C01DA02 |
|
| CASRN |
55-63-0 |
|
| DBBrand |
rectogesic transderm nitro nitrostat nitronet minitran nitrong parenteral nitrospan nitrocap nitro-dur nitrolingual pump spray natispray cellegesic tridil |
|
| DBname |
nitroglycerin |
|
| DBSynonym |
ng nitroglycerine trinitroglycerin ntg tng glyceryl trinitrate nitroglycerin ointment |
|
| Definition |
A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000198 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000281 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0000802 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0001164 http://purl.obolibrary.org/obo/OAE_0000606 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001364 |
|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_51371 http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_66993 http://purl.obolibrary.org/obo/CHEBI_63490 |
|
| InChI |
InChI=1S/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2 |
|
| InChIKey |
InChIKey=SNIOPGDIGTZGOP-UHFFFAOYSA-N |
|
| is metabolised by | ||
| label |
nitroglycerin |
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_71940 http://purl.obolibrary.org/obo/dinto_DB00009 http://purl.obolibrary.org/obo/CHEBI_66876 http://purl.obolibrary.org/obo/CHEBI_584020 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/CHEBI_9139 http://purl.obolibrary.org/obo/dinto_DB00353 http://purl.obolibrary.org/obo/CHEBI_4822 http://purl.obolibrary.org/obo/CHEBI_68845 http://purl.obolibrary.org/obo/dinto_DB01287 http://purl.obolibrary.org/obo/dinto_DB06267 http://purl.obolibrary.org/obo/CHEBI_64318 |
|
| prefixIRI |
obo2:CHEBI_28787 |
|
| prefLabel |
nitroglycerin |
|
| SMILES |
[O-][N+](=O)OCC(CO[N+]([O-])=O)O[N+]([O-])=O |
|
| Synonym |
nitroglycerine trinitroglycerin Nitrostat Nitrolingual 1,2,3-propanetriyl nitrate Nitroglycerin 1,2,3-propanetrioltrinitrate NG glycerol trinitrate propane-1,2,3-triyl trinitrate nitroglycerol Natispray glycerin trinitrate trinitroglycerol glycerol, nitric acid triester 1,2,3-trinitrooxypropane Glyceryl trinitrate C3H5N3O9 Nitromist Transderm Nitro Rectogesic 2,3-bis(nitrooxy)propyl nitrate Nitro-Dur Minitran |
|
| xref |
Drugs.com:http://www.drugs.com/cdi/nitroglycerin.html CiteXplore:11016328 ChEMBL:137493 CiteXplore:23205544 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/nit1296.shtml NIST Chemistry WebBook:55-63-0 DrugBank:DB00727 CiteXplore:22040938 Drugs Product Database (DPD):1926454 National Drug Code Directory:0168-0326-08 ChEBI:28787 PubChem Compound:4510 CiteXplore:11470751 KEGG DRUG:D00515 CiteXplore:23301717 Gmelin:165859 CiteXplore:11943517 Wikipedia:http://en.wikipedia.org/wiki/Nitroglycerin KEGG COMPOUND:C07455 Wikipedia:Glyceryl_trinitrate_(pharmacology) PubChem Substance:46509120 Beilstein:1802063 CASRN:55-63-0 ChEBI:c0061 CiteXplore:9492718 Reaxys:1802063 Wikipedia:Nitroglycerin PharmGKB:PA450644 RxList:http://www.rxlist.com/cgi/generic/ntg.htm CiteXplore:22675243 ChemSpider:4354 |
|
| subClassOf |