Preferred Name |
Alzheimer's disease |
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Synonyms |
[X]Dementia in Alzheimer's disease (disorder) Alzheimer's disease, NOS DAT - Dementia Alzheimer's type Dementia, Presenile [X]Dementia in Alzheimer's disease, unspecified (disorder) [X]Dementia in Alzheimer's disease, unspecified Alzheimers Senile Dementia AD Alzheimer Disease, Late Onset Dementias, Senile Alzheimer Dementia Dementia in Alzheimer's disease Alzheimer's disease Alzheimer's Dementia [X]Dementia in Alzheimer's disease Alzheimer Senile Dementia Alzheimer's disease (disorder) Primary Senile Degenerative Dementia Alzheimers Dementia Dementias, Presenile Alzheimer's Disease Pathway ALZHEIMERS DIS Dementia in Alzheimer's disease (disorder) AD - Alzheimer's disease Presenile Alzheimer Dementia Alzheimers disease ALZHEIMER DIS Dementia of the Alzheimer's type ALZHEIMER DIS EARLY ONSET FOCAL ONSET ALZHEIMERS DIS LATE ONSET ALZHEIMER DIS Senile Dementia, Alzheimer Type Disease, Alzheimer Alzheimer's Disease, Focal Onset Alzheimer Disease, Early Onset Acute Confusional Senile Dementia Dementia in Alzheimer's disease, unspecified (disorder) Alzheimer Type Dementia |
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Definitions |
A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
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ID |
http://www.ebi.ac.uk/efo/EFO_0000249 |
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comment |
A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
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alternative term |
[X]Dementia in Alzheimer's disease (disorder) Alzheimer's disease, NOS DAT - Dementia Alzheimer's type Dementia, Presenile [X]Dementia in Alzheimer's disease, unspecified (disorder) [X]Dementia in Alzheimer's disease, unspecified Alzheimers Senile Dementia AD Alzheimer Disease, Late Onset Dementias, Senile Alzheimer Dementia Dementia in Alzheimer's disease Alzheimer's disease Alzheimer's Dementia [X]Dementia in Alzheimer's disease Alzheimer Senile Dementia Alzheimer's disease (disorder) Primary Senile Degenerative Dementia Alzheimers Dementia Dementias, Presenile Alzheimer's Disease Pathway ALZHEIMERS DIS Dementia in Alzheimer's disease (disorder) AD - Alzheimer's disease Presenile Alzheimer Dementia Alzheimers disease ALZHEIMER DIS Dementia of the Alzheimer's type ALZHEIMER DIS EARLY ONSET FOCAL ONSET ALZHEIMERS DIS LATE ONSET ALZHEIMER DIS Senile Dementia, Alzheimer Type Disease, Alzheimer Alzheimer's Disease, Focal Onset Alzheimer Disease, Early Onset Acute Confusional Senile Dementia Dementia in Alzheimer's disease, unspecified (disorder) Alzheimer Type Dementia |
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definition source |
GeneRIF:12480756 GeneRIF:15152345 GeneRIF:15106838 GeneRIF:16027741 GeneRIF:15060098 GeneRIF:12925530 GeneRIF:15331147 GeneRIF:15722183 GeneRIF:12600718 GeneRIF:12147333 GeneRIF:12084708 GeneRIF:12816543 GeneRIF:15452311 GeneRIF:15144856 GeneRIF:15082170 GeneRIF:15356202 GeneRIF:15967987 GeneRIF:12527400 GeneRIF:15026113 GeneRIF:14572447 GeneRIF:12080182 GeneRIF:13678670 GeneRIF:12023056 GeneRIF:16000144 GeneRIF:15708437 GeneRIF:11840502 GeneRIF:12928512 GeneRIF:12417379 GeneRIF:15212839 GeneRIF:12499843 GeneRIF:12435432 GeneRIF:12707937 GeneRIF:14646594 GeneRIF:16082716 GeneRIF:15546861 GeneRIF:15228592 GeneRIF:12859671 GeneRIF:11971084 DOID:10652 SNOMEDCT:26929004 GeneRIF:15370375 GeneRIF:15953364 GeneRIF:12740599 GeneRIF:12826738 GeneRIF:14651959 GeneRIF:12445809 SNOMEDCT:192164001 GeneRIF:16106215 GeneRIF:11771751 GeneRIF:11278808 GeneRIF:16002400 GeneRIF:11939591 GeneRIF:14978286 GeneRIF:12732730 GeneRIF:16286548 GeneRIF:15192701 GeneRIF:15106847 GeneRIF:15975077 GeneRIF:15024730 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GeneRIF:15094456 GeneRIF:14717705 GeneRIF:15068244 GeneRIF:12928052 GeneRIF:12112088 GeneRIF:15621017 GeneRIF:12641733 GeneRIF:14701757 GeneRIF:11831556 GeneRIF:12223024 GeneRIF:15837559 GeneRIF:15024728 GeneRIF:12787059 GeneRIF:12824768 GeneRIF:11837744 GeneRIF:14675603 GeneRIF:12614934 GeneRIF:15203119 GeneRIF:14739535 GeneRIF:11848684 GeneRIF:12873803 GeneRIF:15601849 GeneRIF:11905990 GeneRIF:15030408 GeneRIF:14625044 GeneRIF:15048650 GeneRIF:14757935 GeneRIF:14663182 GeneRIF:12876265 GeneRIF:15509549 GeneRIF:15313842 GeneRIF:12566926 GeneRIF:11852060 GeneRIF:12142731 GeneRIF:11847218 GeneRIF:12486154 GeneRIF:15091317 GeneRIF:12809550 GeneRIF:12882323 GeneRIF:12707936 GeneRIF:15759131 GeneRIF:15956169 GeneRIF:15804918 GeneRIF:12226093 GeneRIF:16079207 GeneRIF:15016430 GeneRIF:9701251 GeneRIF:12242547 GeneRIF:12650976 GeneRIF:15193763 GeneRIF:12480753 GeneRIF:16174740 GeneRIF:11940690 GeneRIF:12509807 GeneRIF:12133495 GeneRIF:15708435 GeneRIF:11771746 GeneRIF:15823754 GeneRIF:14523088 GeneRIF:12192622 GeneRIF:16130099 GeneRIF:11849768 GeneRIF:14761950 GeneRIF:12770689 GeneRIF:15975076 GeneRIF:14991457 GeneRIF:12514700 GeneRIF:11841602 GeneRIF:12565837 GeneRIF:12025816 GeneRIF:15567486 GeneRIF:14722078 GeneRIF:14523627 GeneRIF:15451372 GeneRIF:15075440 GeneRIF:12483461 GeneRIF:15013567 GeneRIF:15211644 GeneRIF:15364413 GeneRIF:15596614 GeneRIF:12362316 GeneRIF:12609057 GeneRIF:12387451 GeneRIF:15522224 GeneRIF:15313836 GeneRIF:16101387 GeneRIF:15755860 GeneRIF:15781969 GeneRIF:12098640 GeneRIF:15106853 GeneRIF:15087549 GeneRIF:15084795 GeneRIF:11826038 GeneRIF:15050722 GeneRIF:11798857 GeneRIF:12697290 GeneRIF:15737439 GeneRIF:15123740 GeneRIF:12565129 GeneRIF:15464268 GeneRIF:14661818 GeneRIF:15236409 GeneRIF:14521990 GeneRIF:12417381 GeneRIF:12600716 GeneRIF:15944016 GeneRIF:12876460 GeneRIF:15585340 GeneRIF:15147516 GeneRIF:12112084 GeneRIF:15577914 GeneRIF:12692477 GeneRIF:16150694 GeneRIF:12807963 GeneRIF:16098202 GeneRIF:12221172 GeneRIF:15111312 NCIt:C38778 GeneRIF:14746899 GeneRIF:15375590 GeneRIF:12807433 GeneRIF:12145324 GeneRIF:12928051 GeneRIF:12068009 GeneRIF:15068254 GeneRIF:12888622 GeneRIF:16116115 GeneRIF:12480749 GeneRIF:15059642 GeneRIF:12895443 GeneRIF:12508915 GeneRIF:12528817 GeneRIF:15776278 GeneRIF:11897170 GeneRIF:12535780 GeneRIF:12408226 GeneRIF:12489797 GeneRIF:11771749 GeneRIF:12160938 GeneRIF:12459318 GeneRIF:15804423 ICD9:331.0 GeneRIF:12600202 GeneRIF:14991845 GeneRIF:14708344 GeneRIF:11592857 GeneRIF:12890766 GeneRIF:11927634 GeneRIF:12893422 GeneRIF:15453269 GeneRIF:12702875 GeneRIF:16111477 GeneRIF:15456940 GeneRIF:12438920 GeneRIF:15802910 GeneRIF:12111440 GeneRIF:15255951 GeneRIF:15358178 GeneRIF:14657172 GeneRIF:15167696 GeneRIF:15056725 GeneRIF:12116197 GeneRIF:15635706 GeneRIF:12422374 GeneRIF:12605101 GeneRIF:16023140 GeneRIF:12626500 GeneRIF:15184629 GeneRIF:12177374 GeneRIF:12408231 GeneRIF:12531514 GeneRIF:11837743 GeneRIF:12151789 GeneRIF:15465084 GeneRIF:16258844 GeneRIF:12770691 GeneRIF:12499840 GeneRIF:15172102 GeneRIF:15860464 GeneRIF:12614671 GeneRIF:15745979 GeneRIF:12117364 GeneRIF:12914969 GeneRIF:15931081 GeneRIF:15070964 GeneRIF:15728175 GeneRIF:11936240 GeneRIF:11771745 GeneRIF:12200143 GeneRIF:12460603 GeneRIF:12969266 GeneRIF:16179263 GeneRIF:15899246 GeneRIF:11927360 GeneRIF:12939405 GeneRIF:11831025 GeneRIF:15068237 GeneRIF:12742739 GeneRIF:12401548 GeneRIF:16231093 GeneRIF:14519527 GeneRIF:12127670 GeneRIF:12960780 GeneRIF:15882808 GeneRIF:16098915 GeneRIF:12815750 GeneRIF:15716413 GeneRIF:15277615 GeneRIF:12497622 GeneRIF:12111806 GeneRIF:12972157 GeneRIF:12727335 GeneRIF:15893372 GeneRIF:15082191 GeneRIF:15732116 GeneRIF:15175114 GeneRIF:15452128 GeneRIF:15026168 GeneRIF:16116430 GeneRIF:12232784 GeneRIF:15355315 GeneRIF:16102903 GeneRIF:15181247 GeneRIF:15485486 GeneRIF:15530656 GeneRIF:12551918 GeneRIF:15337312 GeneRIF:15263903 GeneRIF:12497631 GeneRIF:12627474 GeneRIF:12459519 GeneRIF:15207261 GeneRIF:12070657 GeneRIF:12218659 SNOMEDCT:192160005 GeneRIF:12368187 GeneRIF:15917098 GeneRIF:14985339 GeneRIF:12107813 GeneRIF:14519529 GeneRIF:15034937 GeneRIF:12032152 NIFSTD:birnlex_2092 GeneRIF:15115757 GeneRIF:12796468 |
|
label |
Alzheimer's disease |
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prefixIRI |
efo:EFO_0000249 |
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prefLabel |
Alzheimer's disease |
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see also | ||
term editor |
James Malone Tomasz Adamusiak |
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subClassOf |
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