loading...| Preferred Name |
Malignant Neoplasm |
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| Synonyms |
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| Definitions |
A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C9305 |
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| ALT_DEFINITION |
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of malignancy. Carcinoma is a malignancy that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a malignancy that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a malignancy that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are malignancies that begin in the cells of the immune system. Central nervous system cancers are malignancies that begin in the tissues of the brain and spinal cord. A group of diseases in which abnormal cells divide without control, invade nearby tissues and may also spread to other parts of the body through the blood and lymph systems. Uncontrolled growth of abnormal cells with potential for metastatic spread. A general term for autonomous tissue growth exhibiting morphologic features of malignancy (e.g. severe atypia, nuclear pleomorphism, tumor cell necrosis, abnormal mitoses, tissue invasiveness) and for which the transformed cell type has not been specifically identified. |
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| code |
C9305 |
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| Contributing_Source |
CDISC CPTAC CTRP FDA GDC MedDRA NICHD |
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| database_cross_reference |
IMDRF:E1801 |
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| definition |
A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. |
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| Display_Name |
Malignant Neoplasm |
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| ICD-O-3_Code |
8000/3 |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C168658 http://purl.obolibrary.org/obo/NCIT_C168656 http://purl.obolibrary.org/obo/NCIT_C168657 http://purl.obolibrary.org/obo/NCIT_C168655 http://purl.obolibrary.org/obo/NCIT_C62596 http://purl.obolibrary.org/obo/NCIT_C77526 http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C168662 http://purl.obolibrary.org/obo/NCIT_C168661 http://purl.obolibrary.org/obo/NCIT_C54450 http://purl.obolibrary.org/obo/NCIT_C19752 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/ncit#oncotree_slim http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C156954 http://purl.obolibrary.org/obo/NCIT_C156953 http://purl.obolibrary.org/obo/NCIT_C158034 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C118464 http://purl.obolibrary.org/obo/NCIT_C88025 http://purl.obolibrary.org/obo/NCIT_C118168 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C156966 |
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| Is_Value_For_GDC_Property |
http://purl.obolibrary.org/obo/NCIT_C178243 http://purl.obolibrary.org/obo/NCIT_C177621 http://purl.obolibrary.org/obo/NCIT_C17103 |
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| label |
Malignant Neoplasm |
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| Legacy Concept Name |
Malignant_Neoplasm |
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| Maps_To |
Malignant neoplasm of other and ill-defined sites: Lower limb Neoplasm, malignant Malignant neoplasm, primary site unknown, so stated Tumor, malignant, NOS Other malignant neoplasm of unspecified site Malignant neoplasm of other and ill-defined sites Unclassified tumor, malignant Malignant neoplasm, without specification of site Malignant neoplasm, unspecified Malignant neoplasm of other specified sites Malignant neoplasm of other and ill-defined sites: Overlapping lesion of other and ill-defined sites Malignant neoplasm without specification of site 8000/3 Cancer Malignancy |
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| Neoplastic_Status |
Malignant |
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| Preferred_Name |
Malignant Neoplasm |
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| prefixIRI |
NCIT:C9305 |
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| prefLabel |
Malignant Neoplasm |
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| Semantic_Type |
Neoplastic Process |
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| UMLS_CUI |
C1861853 |
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| subClassOf |