loading...| Preferred Name |
Paroxysmal Nocturnal Hemoglobinuria |
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| Synonyms |
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| Definitions |
A rare acquired hematologic disorder characterized by hemolytic anemia, dark-colored urine due to the release of hemoglobin in the blood, and thrombosis. The episodes of hemolysis tend to occur at night. It is caused by a somatic mutation in the glycosylphosphatidylinositol biosynthesis gene. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C61233 |
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| ALT_DEFINITION |
A rare disorder in which red blood cells are easily destroyed by certain immune system proteins. Symptoms include blood clots, and red or brownish urine in the morning. Aplastic anemia (decreased production of blood cells) may lead to PNH, and people with PNH are at increased risk of acute myelogenous leukemia. |
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| code |
C61233 |
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| Contributing_Source |
Cellosaurus CTRP |
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| definition |
A rare acquired hematologic disorder characterized by hemolytic anemia, dark-colored urine due to the release of hemoglobin in the blood, and thrombosis. The episodes of hemolysis tend to occur at night. It is caused by a somatic mutation in the glycosylphosphatidylinositol biosynthesis gene. |
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| Display_Name |
Paroxysmal Nocturnal Hemoglobinuria |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Paroxysmal Nocturnal Hemoglobinuria |
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| Legacy Concept Name |
Paroxysmal_Nocturnal_Hemoglobinuria |
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| Preferred_Name |
Paroxysmal Nocturnal Hemoglobinuria |
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| prefixIRI |
NCIT:C61233 |
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| prefLabel |
Paroxysmal Nocturnal Hemoglobinuria |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0024790 |
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| subClassOf |