loading...| Preferred Name |
Eplerenone |
|
| Synonyms |
|
|
| Definitions |
A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerenone is used in the treatment of hypertension and congestive heart failure. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47513 |
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| CAS_Registry |
107724-20-9 |
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| CHEBI_ID |
CHEBI:31547 |
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| Chemical_Formula |
C24H30O6 |
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| code |
C47513 |
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| Contributing_Source |
FDA |
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| definition |
A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerenone is used in the treatment of hypertension and congestive heart failure. |
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| FDA_UNII_Code |
6995V82D0B |
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| in_subset | ||
| label |
Eplerenone |
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| Legacy Concept Name |
Eplerenone |
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| NCI_Drug_Dictionary_ID |
741940 |
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| PDQ_Closed_Trial_Search_ID |
741940 |
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| PDQ_Open_Trial_Search_ID |
741940 |
|
| Preferred_Name |
Eplerenone |
|
| prefixIRI |
NCIT:C47513 |
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| prefLabel |
Eplerenone |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0961485 |
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| subClassOf |