Preferred Name |
Deferoxamine Mesylate |
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Synonyms |
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Definitions |
The mesylate salt of an iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine chelates iron from intra-lysosomal ferritin and ferrioxamine, a water-soluble complex excreted by the kidneys and in the feces via the bile. This agent does not readily chelate iron bound to transferrin, hemoglobin, myoglobin or cytochrome. |
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ID |
http://purl.obolibrary.org/obo/NCIT_C417 |
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CAS_Registry |
138-14-7 |
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CHEBI_ID |
CHEBI:31460 |
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Chemical_Formula |
C25H48N6O8.CH4O3S |
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code |
C417 |
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Contributing_Source |
CTRP FDA |
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definition |
The mesylate salt of an iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine chelates iron from intra-lysosomal ferritin and ferrioxamine, a water-soluble complex excreted by the kidneys and in the feces via the bile. This agent does not readily chelate iron bound to transferrin, hemoglobin, myoglobin or cytochrome. |
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Display_Name |
Deferoxamine Mesylate |
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FDA_UNII_Code |
V9TKO7EO6K |
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Has_Free_Acid_Or_Base_Form | ||
Has_Target | ||
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 http://purl.obolibrary.org/obo/NCIT_C173381 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 |
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Is_Value_For_GDC_Property | ||
label |
Deferoxamine Mesylate |
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Legacy Concept Name |
Deferoxamine_Mesylate |
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Maps_To |
Deferoxamine Mesylate |
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NCI_Drug_Dictionary_ID |
41696 |
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NSC Number |
644468 |
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PDQ_Closed_Trial_Search_ID |
41696 |
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PDQ_Open_Trial_Search_ID |
41696 |
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Preferred_Name |
Deferoxamine Mesylate |
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prefixIRI |
NCIT:C417 |
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prefLabel |
Deferoxamine Mesylate |
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Semantic_Type |
Organic Chemical Pharmacologic Substance |
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UMLS_CUI |
C0011148 |
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subClassOf |